PSA Flashcards
3 CCB side effects
Peripheral oedema and Facial flushing and headache
Antimuscarinic side effects and 2 drug classes that ask for them
Dry mouth, double vision, tachycardia
Amitryptiline and Cyclizine
2 drug classes causing Neutropaenia
Carbamazepine and Thionamides
Phenytoin side effects
Dysarthria and Gum hyperplasia
Ataxia, Nystagmus and Peripheral Neuropathy
Teratogenic
Steroid effect on WCC
Neutrophilia
Acei Side effects
Cough and Angiodema
Up to 20% Creatinine rise is normal
7 drugs causing hyperkalaemia
Ciclosporin, Tacrolimos, Acei, Arb, Ald ant, Heparins, and NSAID’s
Most common side effect of amoxicillin vs Co-amox
Diarrhoe and Rash vs Diarrhoea, Rash, and Jaundice/Hepatic dysfunction
3 drugs causing diarrhoea
Amox, Omeprazole, Alendronic acid
What common cardio drug to avoid in PVD
Beta blocker
What cardio drug to avoid in heart failure
Cardioselective CCB’s and Flecanide
Which UTI antibiotics to avoid in CKD/AKI?
Nitro - Generally avoid and Trimethoprin - Dose adjust
Warfarin - Target INR’s
2-3 for Most
3-4 for PE on AC, Recurrent DVT, or mechanical valve
<1.5 for surgery - give Vit K to lower if needed
9 drugs to stop in AKI
ACEi, ARB, Spiro, NSAID
Gent and Vanc
Allopurinol and Metformin
Lithium
3 Drugs at night
Statins, Acei, TCA’s
3 Drugs in morning
Diuretics, Pred, Bisphosphonates w/breakfast
Breakthrough pain dose and route
1/6th dose and oral, nasal, buccal, or sublingual
When switching opiod drugs what is the relevence of PRN
Even in constant pain, if drug is PRN, swap to PRN drug
6 Psoriasis exacebators
B-blockers, Lithium, Anti-malarias,
NSAID’s, AceI,
Inflximab
Alcohol
Safest opiods in renal disease?
Fentanyl and buprenorphine
Anti-D dosing changes
In elderly are lower
How to pick anti- emetics
- Default Cyclizine - Except in heart failure
- Metoclopramide - Avoid in parkinsons or obstruction or recent GI surgery or on other antipsychotics
- Donperidone - Fine in parkinsons, but avoid in GI obstuction, bleeds, or surgery
- Ondansetron - Save for cancer
Transfusions
When to use IV iron?
When to give Red cell transfusions?
When to give Platelet transfusions
- Iron
- IV only in major bleed or Surgeyr happening soon
- Red Cells
- Hb < 70 in normal, Less than 80 in ACS
- PLatelets
- Count < 30, or < 100 in Severe bleed/Bleeding in key site (e.g. CNS)
What do if drug levels are low
- If no clinical improvement Increase dose
- If clinical improvement dose stays same because clinical effect is most important
What do if drug levels are high?
- If no toxicity - Reduce dose
- If toxicity or very high - Omit dose for a few days
- Gentamicin - If no signs of toxicity. Make doses less frequent, rather than reducing dose.
When to take levels?
- Ciclosporin - Trough levels pre dose
- Phenytoin - Trough levels pre dose
- Digoxin - Serum levels at least 6 hours post dose (Only monitor in renal impairment patients only)
- Lithium - Serum concentration checked 12 hours post dose
What to check if on COCOP or HRT
Blood pressure
3 drugs contraindicated in Asthma
NSAIDs/Aspirin, Adenosine, beta blockers
