PSA

Question 1

3 CCB side effects

Answer 1

Peripheral oedema and Facial flushing and headache

Question 2

Antimuscarinic side effects and 2 drug classes that ask for them

Answer 2

Dry mouth, double vision, tachycardia

Amitryptiline and Cyclizine

Question 3

2 drug classes causing Neutropaenia

Answer 3

Carbamazepine and Thionamides

Question 4

Phenytoin side effects

Answer 4

Dysarthria and Gum hyperplasia
Ataxia, Nystagmus and Peripheral Neuropathy
Teratogenic

Question 5

Steroid effect on WCC

Answer 5

Neutrophilia

Question 6

Acei Side effects

Answer 6

Cough and Angiodema

Up to 20% Creatinine rise is normal

Question 7

7 drugs causing hyperkalaemia

Answer 7

Ciclosporin, Tacrolimos, Acei, Arb, Ald ant, Heparins, and NSAID’s

Question 8

Most common side effect of amoxicillin vs Co-amox

Answer 8

Diarrhoe and Rash vs Diarrhoea, Rash, and Jaundice/Hepatic dysfunction

Question 9

3 drugs causing diarrhoea

Answer 9

Amox, Omeprazole, Alendronic acid

Question 10

What common cardio drug to avoid in PVD

Answer 10

Beta blocker

Question 11

What cardio drug to avoid in heart failure

Answer 11

Cardioselective CCB’s and Flecanide

Question 12

Which UTI antibiotics to avoid in CKD/AKI?

Answer 12

Nitro - Generally avoid and Trimethoprin - Dose adjust

Question 13

Warfarin - Target INR’s

Answer 13

2-3 for Most
3-4 for PE on AC, Recurrent DVT, or mechanical valve
<1.5 for surgery - give Vit K to lower if needed

Question 14

9 drugs to stop in AKI

Answer 14

ACEi, ARB, Spiro, NSAID
Gent and Vanc
Allopurinol and Metformin
Lithium

Question 15

3 Drugs at night

Answer 15

Statins, Acei, TCA’s

Question 16

3 Drugs in morning

Answer 16

Diuretics, Pred, Bisphosphonates w/breakfast

Question 17

Breakthrough pain dose and route

Answer 17

1/6th dose and oral, nasal, buccal, or sublingual

Question 18

When switching opiod drugs what is the relevence of PRN

Answer 18

Even in constant pain, if drug is PRN, swap to PRN drug

Question 19

6 Psoriasis exacebators

Answer 19

B-blockers, Lithium, Anti-malarias,
NSAID’s, AceI,
Inflximab
Alcohol

Question 20

Safest opiods in renal disease?

Answer 20

Fentanyl and buprenorphine

Question 21

Anti-D dosing changes

Answer 21

In elderly are lower

Question 22

How to pick anti- emetics

Answer 22

• Default Cyclizine - Except in heart failure
• Metoclopramide - Avoid in parkinsons or obstruction or recent GI surgery or on other antipsychotics
• Donperidone - Fine in parkinsons, but avoid in GI obstuction, bleeds, or surgery
• Ondansetron - Save for cancer

Question 23

Transfusions
When to use IV iron?
When to give Red cell transfusions?
When to give Platelet transfusions

Answer 23

• Iron
• IV only in major bleed or Surgeyr happening soon
• Red Cells
• Hb < 70 in normal, Less than 80 in ACS
• PLatelets
• Count < 30, or < 100 in Severe bleed/Bleeding in key site (e.g. CNS)

Question 24

What do if drug levels are low

Answer 24

• If no clinical improvement Increase dose

- If clinical improvement dose stays same because clinical effect is most important

Question 25

What do if drug levels are high?

Answer 25

• If no toxicity - Reduce dose
• If toxicity or very high - Omit dose for a few days
• Gentamicin - If no signs of toxicity. Make doses less frequent, rather than reducing dose.

Question 26

When to take levels?

Answer 26

• Ciclosporin - Trough levels pre dose
• Phenytoin - Trough levels pre dose
• Digoxin - Serum levels at least 6 hours post dose (Only monitor in renal impairment patients only)
• Lithium - Serum concentration checked 12 hours post dose

Question 27

What to check if on COCOP or HRT

Answer 27

Blood pressure

Question 28

3 drugs contraindicated in Asthma

Answer 28

NSAIDs/Aspirin, Adenosine, beta blockers