PSA Flashcards

1
Q

Drugs to stop in acute renal failure

A

ACEI/ARB
Metformin
Allopurinol (reduce)
NSAIDS

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2
Q

Drugs causing hypoglycaemia

A

Pioglitazone
Sulphonylureas (gliclazide, tolbutamide)
Insulin

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3
Q

Drugs causing urinary retention

A
Anticholonergics
GA
Benzos
NSAIDs
CCBs
Anitihistamines
Alcohol
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4
Q

Drugs causing confusion

A
Opiates
Anticholinergics
Antipsychotics
Antidepressants
Anticolvulsants
Antihistamines
Metacloperamide
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5
Q

Starting dose simvastatin

A

Primary prevention - 20mg ON

Established CVD - 80mg ON

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6
Q

HTN - First Line Drugs

A

<55 - ACEI
>55 - CCB

Afrocaribean - CCB
Diabetic - ACEI

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7
Q

Folic acid doses

A

Low risk - 400mcg

High risk - 5mg

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8
Q

Bisphosphonates - patient advice

A

Take 30 mins before food or other drugs

Sit upright for 30 mins

Take with plenty of water

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9
Q

Gentamycin - interpretation of levels

A

Peak level high/low - change dose

Trough level high/low - change frequency

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10
Q

CYP Inducers

A
Phenytoin
Carbamazepine
Barbiturates
Rifampacin
Alcohol (chronic)
Sulphonyureas (gliclazide)
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11
Q

CYP Inhibitors

A
Grapefruit
Omeprazole
Disulfiram
EtOH (acute)
Valproate
Isoniazid
Ciprfloxacin + Cimetidine
Erythromycin (and other macrolides)
Sulphonamides
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12
Q

Lithium - monitoring

A

Before starting: BMI, ECG, U&Es, FBC
6/12: BMI, U&Es, TFTs

Levels - minimum 3/12

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13
Q

Drugs causing neutropenia

A

Chemotherapy

Carbamazepine

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14
Q

Surgical VTE Prophylaxis with a needle phobia

A

Apixaban 2.5mg BD
or
Rivaroxiban 10mg OD

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15
Q

Drugs causing hyperkalaemia

A

I SHAT one when I saw they had hyperkalaemia

SHAT
Spironolactone / Eplerenone
Heparins
ACEi
Tacrolimus / Ciclosporin
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16
Q

Surgery - drugs to stop

A

Anti platelets (7/7)
Hypoglycaemics (morning of)
OCP/HRT (4/52)
Warfarin (5/7)

17
Q

Drugs causing hyponatraemia

A

Thiazides
SSRIs
ACEI/ARB

18
Q

INR >1.5 before surgery

A

phytomenadione (vitamin K) 5mg PO

19
Q

Daily potassium requirements

A

1mmol/kg/day

20
Q

Missed OCP pills

A

Take as soon as remember
If this is the next day then take two pills that day
No other contraception needed

21
Q

Statins - myalgia and raised CK

A

If CK > 5x upper limit then stop

If symptoms resolve then re-start at lower dose

22
Q

Causes of ankle oedema

A

Amlodipine

Naproxen

23
Q

Initial management of DKA

A

Fluid resus - 1l 0.9% NaCl over first hour
Fixed rate insulin infusion - Actrapid 0.1u/kg/hr IV
Continue current long-acting insulin

24
Q

Management of Neuroleptic Malignant Syndrome

A

Procyclidine

25
Q

Analgaesia in renal failure

A

Avoid NSAIDs

Oxycodone > morphine - has hepatic metabolism so won’t accumulate