PSA Flashcards
What should you check before prescribing metformin?
Renal Function
Which antibiotics may lower seizure threshold in epilepsy?
Quinolones (ie. Ciprofloxacin)
What is the dose of adrenaline in cardiac arrest?
1:1000 10ml
Which CCB most exaggerates heart failure?
Verapamil
Can doxycycline be used in pregnancy?
No
How is cocaine overdose managed?
Benzos
Which complication is most commonly associated with aminoglycosides such as gentamicin?
Nephrotoxicity
Which antibiotics may cause long QT?
Macrolides eg Clarithromycin
Which drugs should be avoided in renal failure?
NSAID
Metformin
Lithium
Tetracycline, Nitrofurantoin
Which drugs can treat motion sickness
Hyoscine
Cyclizine
Promethazine
When would you give IV sodium bicarbonate in TCA overdose?
pH <7.1
QRS >160 ms
Arrhythmias
Hypotension
In which patient group is diclofenac contraindicated?
Those with cardiovascular disease
Which antibiotics are contraindicated in those with G6PD Deficiency (Heinz bodies on smear)
Quinolones (Ciprofloxacin)
How is heparin monitored in patients with renal impairment?
Anti Factor Xa levels
How is organophosphate poisoning managed?
Atropine
What are the most common side effects of calcium channel blockers?
Headache, flushing, ankle oedema
Which drugs can cause hypomagnesaemia?
PPIs
Diuretics
Which drug can be used to manage tremor in drug-induced parkinsonism?
Procyclidine
What would be used to alleviate pain in cases of raised ICP due to brain cancer?
Dexamethasone
Which cvs drug can worsen psoriasis?
Beta Blockers
Which class of drugs may worsen Parkinsonism?
Antipsychotics (Oral lorazepam)
What should be started in T2DM in a patient with CVD?
Metformin and an SGLT2 Inhibitor as first line
Which important side effect is most important to counsel patients of when using clindamycin?
C.Dif risk
How is acute relapse managed in MS?
Methylprednisolone (IV or Oral)
What would you give for secondary prevention following stroke if Diclofenac is contraindicated?
Aspirin and Dipyridamole
Duloxetine and renal failure?
Contraindicated GFR under 30
Duloxetine and renal failure?
Contraindicated GFR under 30
45yo M. HTN. T2DM. Renal Artery Stenosis. Antihypertensive?
CCB. ACEi contraindicated in renovascular disease
Which macrolide should be used in pregnancy?
Erythromycin
What is an importnt side effect of metoclopramide to counsel male patients on?
Galactorrhoea
In whom is adenosine contraindicated?
Asthmatics due to bronchospasm
Name a contraindication to triptan use in migraine prophylaxis.
CVD
When is pioglitazone contraindicated?
Heart Failure
What are the first two lines of MRSA management?
Vancomycin -> Linezolid
Which tests must. be performed before starting treatment for TB?
U&Es, LFTs, FBC, Vision Testing
What is an alternative aldosterone antagonist if spironolactone is not tolerated in a patient with chronic congestive heart failure?
Eplerenone
What is the first line treatment for CML?
Imatinib - Tyrosine Kinase Inhibitor
Gonorrhoea management if patient doesn’t like needles?
Oral Cefixime
Oral Azithromycin
How would you treat chlamydia in pregnancy?
Azithromycin, erythromycin, amoxicillin
Which drugs most commonly cause angioedema?
ACEi
What is an important side effect of the induction agent etomidate?
Adrenal Suppression
What are the main side effects of tamsulosin?
Dizziness and Postural hypotension
When is Pioglitazone contraindicated?
Bladder Cancer
When should calcium/iron supplements be taken in a patient on thyroxine replacement?
At least 4 hours after levothyroxine dose
Which tb med causes orange tears/urine?
Rifampicin
Which dmard can patients allergic to aspirin also be sensitive to?
Sulfasalazine
What is a key complication of rapid vancomycin infusion?
Red Man Syndrome
What should be prescribed for a diabetic patient with urine ACR over 3?
ACEi or ARB for renal protection
What is the first line treatment for acute flares of acute intermittent porphyria?
Haem Arginate
What should you take a statin?
Last thing at night
What is the most common side effect of isotretinoin?
Dry skin
Name a severe ocular side effect of hydroxychloroquine
Bull’s Eye Retinopathy