Protozoan Infections - Treatments Flashcards

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1
Q

Giardia lamblia

A

Metronidazole

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2
Q

Entamoeba histolytica

A
  • Trophozoites: metronidazole
  • Cysts: paromomycin, iodoquinol
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3
Q

Cryptosporidium parvum

A

Nitazoxanide, spiramycin

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4
Q

Toxoplasma gondii

A
  • Treatment: spiramycin, pyrimethamine + sulfadiazine
  • Prevention: TMP/SMX (trimethoprim/sulfamethoxazole)
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5
Q

Trypanosoma brucei

A
  • T. brucei gambiense
  • T. brucei rhodesiense

Treatment:

  • Acute (for peripheral blood infection): suramin
  • Chronic (for CNS infection): melarsoprol
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6
Q

Naegleria fowleri

A

Amphotericin B

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7
Q

Trypanosoma cruzi

A

Acute: nifurtimox, benzidazole

Chronic: none

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8
Q

Babesia

A

Atovaquone + azithromycin

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9
Q

Plasmodium species

A

Treatment:

  • Chloroquine (for sensitive species); if resistant, use mefloquine or atovaquone/proguanil
  • If life-threatening, use intravenous quinidine or artesunate (artemisinin) (test for G6PD deficiency)
  • For P. vivax/ovale, add primaquine for hypnozoite (test for G6PD deficiency)
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10
Q

Leishmania

A
  • L. braziliensis
  • L. donovani

Treatment: sodium stibogluconate, amphotericin B

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11
Q

Trichomonas vaginalis

A

Metronidazole

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12
Q

Balantidium coli

A
  • Metronidazole
  • Tetracycline
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