Protozoa Flashcards
Giardia lamblia, giardiasis
flagellated protozoan; water and food contamination; anal-oral; ingestion of cysts; worldwide, 1-2 weeks, abdominal pain and bloating, flatulence, greasy diarrhea, treatment: Metronidazole
Trypanosoma cruzi
flagellated protozoan, transmitted via kissing bug, South America;
Chagas Disease
caused by Trypanosoma cruzi, Romana’s sign, chronic phase for life, enlarged heart, arrythmia, digestive tract problems
Toxoplasma gondii
apicomplexan protozoan; definitive host: domestic cat; cysts ingested-cat feves or undercooked meat; worldwide and infection usually sporadic and asymptomatic
Cyst general pathway
Cyst -> Oocysts -> tachyzoites (neural, muscle tissue) -> tissue cyst bradyzoites (reactivated for encephalitis)
Toxoplasmosis
tachyzoites spread to other organs - brain, lungs, liver, eyes; limited by competent immune system
Plasmodium species (Malaria)
apicomplexan protozoan, Definitive host: Anopheles mosquitos, spread during blood meal, endemic to tropic areas
Malaria symptoms
2 week intubation; cyclic fever and chills; anemia; affects the most RBC
Transmission of helminths
fecal-oral route, penetration of skin, bite by infected blood sucking insect vector
Trematodes-flukes
hermaphrodites, eggs develop into larvae and must pass through one intermediate host to be infectious again; develop in intestine, lungs, liver, and blood vessels; develops in snails so humans are infected through water
Schistomsoma species
trematode-“blood fluke”; male and female worms joined together; Definitive host-humans; intermediate: snails; mature in liver; causes schistosomiasis
Schistosomiasis
Acute: swimmer’s itch- pruritic popular rash usually on legs and feet, site of cercariae penetration;
Chronic intestine: abdominal pain, poor appetite, diarrhea
Cestodes- tapeworms
Scolex, suckers attach to intestinal wall; acquired by eating undercooked or raw meat; relatively harmless
Taenia solium
tapeworms; scloex: head with suckers/hooks for attachment to intestines; Defintive host: humans, ingestion of cysts; Intermediate hosts: pigs
Nermatodes: roundworm
sexes are separate; most species liberate fertilized eggs from host; some are highly specific to humans; other require non-human animal host