Proton Pump Inhibitors (PPI) Flashcards
1
Q
Prototype
A
Omeprazole
2
Q
MOA
A
Reduce acid secretion in stomach by binding to enzyme. Puts a cork in the system
3
Q
Suffix
A
Prazole
4
Q
Side effects
A
Headache, nausea, diarrhea, rash, abdominal pain
Long term use increases gastric cancer, kidney injury, bone loss
5
Q
Considerations
A
Don’t crush or chew
Take 1 hr before meal
6
Q
Primary use
A
4-8 week GERD or peptic ulcer treatment
