Protocols Flashcards
Indications- Adrenaline
Anaphylaxis OR severe allergic reaction
Severe life-threatening bronchospasm OR silent chest. (Patients must only be able to speak in single words AND/OR have haemodynamic compromise AND/OR an ALOC.)
Bradycardia with poor perfusion (unresponsive to atropine AND/OR TCP)
Cardiac arrest
Croup (with stridor at rest)
Shock unresponsive to adequate fluid resuscitation (excluding haemorrhagic cause)
Contraindications-Adrenaline
KSAR
Precautions-Adrenaline
Hypovolaemic shock
Hypertension
Patients taking monoamine oxidase inhibitors (MAOIs)
Side effects -Adrenaline
Anxiety
Hypertension
Palpitations/tachyarrhythmias
Pupil dilation
Adrenaline adult dosages-anaphylaxis
IMi 500 mcg
Repeated at 5 minutes if no improvement as per ARC guidelines
NEB 5 mg
Single dose only
May be administered for minor facial or tongue swelling thought to be allergic in origin. If stridor present, IM or IV adrenaline must be administered.
IV/IO 20–50mcg (ICP only)
Repeated at 1 minute intervals
No maximum dose
Adrenaline adult dosages- Severe life-threatening bronchospasm OR silent chest
(patients must only be able to speak in single words AND/OR have haemodynamic compromise AND/OR an ALOC.)
IM - 500 mcg
Repeated at 5 minutes if no improvement as per ARC guidelines
IV/IO - 20 mcg (ICP)
Repeated at 1 minute intervals.
No maximum dose
Adrenaline adult dosages - Bradycardia with poor perfusion (unresponsive to atropine AND/OR TCP)
IV/IO 20 mcg (ICP)
Repeated at 1 minute intervals. No maximum dose
Adrenaline adult dosages - Cardiac arrest
IV/IO 1mg
Repeated at 3-5 minute intervals as per ARC guidelines
No maximum dose
Adrenaline adult dosages - Shock unresponsive to adequate fluid resuscitation (excluding haemorrhagic cause)
IV/IO 20 mcg (ICP)
Repeated at 1 minute intervals. No maximum dose
Adrenaline paediatric dosages
Anaphylaxis OR severe allergic reaction
IM = or > 6 years - 300 mcg
Repeated at 5 minutes if no improvement as per ARC guidelines
< 6 years - 150 mcg
Repeated at 5 minutes if no improvement as per ARC guidelines
NEB 5 mg
Single dose only.
May be administered for minor facial or tongue swelling thought to be allergic in origin. If stridor present, IM or IV adrenaline must be administered.
IV/IO 2 mcg/kg (ICP)
Single dose not to exceed 50 mcg. Repeated at 2 minute intervals.
Adrenaline paediatric dosages -
Severe life-threatening bronchospasm OR silent chest
(patients must only be able to speak in single words AND/OR have haemodynamic compromise AND/OR an ALOC.)
IM = or > 6 years - 300 mcg
Repeated at 5 minutes if no improvement as per ARC guidelines
< 6 years - 150 mcg
Repeated at 5 minutes if no improvement as per ARC guidelines
IV/IO 2 mcg/kg (ICP)
Single dose not to exceed 50 mcg. Repeated at 2 minute intervals. No maximum dose
Adrenaline paediatric dosages - Cardiac arrest
IV 10 mcg/kg (ICP)
as per ARC guidelines Repeated at 3-5 minute intervals.
No maximum dose
IO 10 mcg/kg
as per ARC guidelines Repeated at 3-5 minute intervals. No maximum dose
Adrenaline paediatric dosages - Croup (with stridor at rest)
NEB 5 mg
Single dose only
Adrenaline paediatric dosages - Shock unresponsive to adequate fluid resuscitation
(excluding haemorrhagic cause)
IV/IO 2 mcg/kg (ICP)
Single dose not to exceed 50 mcg. Repeated at 2 minute intervals.
No maximum dose
Adrenaline paediatric dosages - Bradycardia with poor perfusion
(unresponsive to atropine AND/OR TCP)
IV/IO 2 mcg/kg (ICP)
Single dose not to exceed 50 mcg. Repeated at 2 minute intervals.
No maximum dose
Indications -Amiodarone
Cardiac arrest (refractory VF or pulseless VT)
Contra-indications - Amiodarone
Nil in Cardiac arrest (refractory VF or pulseless VT)
Precautions - Amiodarone
Cardiac arrest (refractory VF or pulseless VT): - concomitant use of anti-arrhythmics that prolong the QT interval - thyroid disease
Side effects - Amiodarone
Hypotension
Bradycardia
Nausea and/or vomiting
Peripheral paraesthesia
Amiodarone adult dosages - Cardiac arrest (refractory VF or pulseless VT) as per ARC guidelines
IV 300 mg
Slow push over 2 minutes.
Repeat once at 150 mg after 5 minutes Total maximum dose – 450 mg
IO 300 mg
Slow push over 2 minutes.
Repeated once at 150 mg after 5 minutes
Total maximum dose – 450 mg
Amiodarone paediatric dosages - Cardiac arrest (refractory VF or pulseless VT) as per ARC Guidelines
IV 5 mg/kg (ICP)
Slow push over 2 minutes.
Single dose only
Syringe preparation: Mix 150 mg (3 mL) of amiodarone with 12 mL of glucose 10% (totalling 15 mL) in a 20 mL syringe to achieve a final concentration of 10 mg/mL.
IO 5 mg/kg
Slow push over 2 minutes.
Single dose only
Syringe preparation: Mix 150 mg (3 mL) of amiodarone with 12 mL of glucose 10% (totalling 15 mL) in a 20 mL syringe to achieve a final concentration of 10 mg/mL.
Indications -Aspirin
Suspected ACS
Acute cardiogenic pulmonary oedema
Contraindications - Aspirin
KSAR to aspirin or other NSAIDs Chest pain associated with psych stimulant overdose Bleeding disorders Current GI bleeding or peptic ulcers Patients < 12 years
Precautions - Aspirin
Possible aortic aneurysm or any other condition that may require surgery
Pregnancy
History of GI bleeding or peptic ulcers
Concomitant anticoagulant therapy (excluding clopidogrel)
Side effects - Aspirin
Epigastric pain/discomfort Nausea and/or vomiting Gastritis GI bleeding NSAID induced bronchospasm
Aspirin adult dosages -
Suspected ACS
Acute cardiogenic pulmonary oedema
PO >12 years - 300 mg
Chewed and followed by a small sip of water (where possible)
Indications- Atropine
Bradycardia (with poor perfusion – Pre Adrenaline)
Envenomation (with increased parasympathetic activity)
Hypersalivation (with ketamine administration)
Organophosphate toxicity (with cardiac AND/OR respiratory compromise).
Contraindications - Atropine
KSAR
Precautions -Atropine
Atrial flutter
Atrial fibrillation
AMI
Glaucoma
Side effects - Atropine
Agitation Hallucinations Dilated pupils Dry mouth/dry skin/reduced bronchial and gastric secretions Tachycardia
Atropine adult dosage -
Bradycardia (with poor perfusion)
IV/IO 600 mcg (ICP)
Repeated once after 2 minutes
Total maximum dose 1.2 mg
Atropine adult dosages - Envenomation (with increased parasympathetic activity)
IM 1.2 mg (ICP)
Repeated at 5 minute intervals.
No maximum dose
IV/IO 1.2 mg (ICP)
Repeated at 5 minute intervals.
No maximum dose
Atropine adult dosages - Hypersalivation (with ketamine administration)
IV/IO 600 mcg (ICP)
Single dose only
Atropine adult dosage - Organophosphate toxicity (with cardiac AND/OR respiratory compromise)
IM 1.2 mg (ICP)
Repeated at 5 minute intervals.
No maximum dose
IV/IO 1.2 mg (ICP)
Repeated at 5 minute intervals.
No maximum dose
Atropine paediatric dosage - Bradycardia (with poor perfusion)
IV/IO 20 mcg/kg (ICP)
Single dose not to exceed 600 mcg.
Repeated once after 2 minutes.
Total maximum dose 40 mcg/kg
Atropine paediatric dosage -
Envenomation (with increased parasympathetic activity)
Organophosphate toxicity (with cardiac AND/OR respiratory compromise)
IM 20 mcg/kg (ICP)
Single dose not to exceed 600 mcg.
Repeated at 5 minute intervals.
No maximum dose
IV/IO 20 mcg/kg (ICP)
Single dose not to exceed 600 mcg.
Repeated at 5 minute intervals.
No maximum dose
Atropine paediatric dosage -
Hyper-salivation (with ketamine administration)
IV/IO 20 mcg/kg (ICP)
Single dose only, not to exceed 600 mcg
Indications - Calcium Gluconate 10%
Suspected hyperkalaemic cardiac arrest.
Severe hyperkalaemia (with haemodynamic compromise AND/OR significant cardiac rhythm disturbance)
Calcium channel blocker toxicity
Hypotension associated with a magnesium infusion (that fails to respond to intravenous fluid therapy
Contraindications - Calcium Gluconate 10%
KSAR
Digoxin (digitalis) overdose
Precautions - Calcium Gluconate 10%
Respiratory acidosis
Side effects - Calcium Gluconate
Suspected hyperkalaemic cardiac arrest:
nil
For all other SJANT indications IV administration may cause: syncope hypotension bradycardia cardiac dysrrhythmias cardiac arrest
Calcium Gluconate 10% adult dosage-
Suspected hyperkalaemic cardiac arrest
Severe hyperkalaemia
(with haemodynamic compromise ANT/OR significant cardiac rhythm disturbance)
Calcium channel blocker toxicity
Hypotension associated with a magnesium infusion (that fails to respond to intravenous fluid therapy)
IV/IO 10 mL (ICP)
Slow push over 2 minutes
Repeated once at 10 minutes
Calcium Gluconate 10% paediatric dosages-
Suspected hyperkalaemic cardiac arrest
Severe hyperkalaemia (with haemodynamic compromise ANT/OR significant cardiac rhythm disturbance)
Calcium channel blocker toxicity
Hypotension associated with a magnesium infusion (that fails to respond to intravenous fluid therapy)
IV/IO 0.2 mL/kg (ICP)
Slow push over 2 minutes
Repeated once at 10 minutes
Indications - Ceftriaxone
Suspected meningococcal septicaemia (with a non- blanching petechial AND/OR purpuric rash).
Contraindications - Ceftriaxone
< 1 month old
KSAR to cephalosporin drugs
Known anaphylaxis or severe allergic reaction to penicillin based drugs – (isolated minor drug rash attributed to penicillin does not contraindicate the use of ceftriaxone.
Precautions - Ceftriaxone
Nil
Side effects - Ceftriaxone
Nausea and/or vomiting
Pain at the IM administration site
Ceftriaxone Adult dosages
Suspected meningococcal septicaemia
with a non-blanching petechial AND/OR purpuric rash
IM 4g
The solution should be administered by deep intramuscular injection
Syringe preparation:
Reconstitute two 2 gram vials with approximately 2.4mL of water for injection to achieve a final concentration of
4 g/4 mL (1 g/mL).
IV 4g Slow push over 3 - 5 minutes Syringe preparation: Reconstitute two 2 gram vials with approximately 8.4 mL of water for injection to achieve a final concentration of 4g/10 mL (400 mg/mL)
Ceftriaxone Paediatric dosages -
Suspected meningococcal septicaemia
with a non-blanching petechial AND/OR purpuric rash
IM 100 mg/kg (> 1 month)
The solution should be administered by deep
intramuscular injection
Syringe preparation:
Reconstitute 2 g of ceftriaxone with 3.6 mL of water for injection to achieve a final concentration of
2 g/4 mL (500 mg/mL)
IV 100 mg/kg (> 1 month) -ICP Slow push over 3 - 5 minutes Syringe preparation: Reconstitute 2 g of ceftriaxone with 9.6 mL of water for injection to achieve a final concentration of 2 g/10 mL (200 mg/mL)
Indications - Fentanyl
Significant pain
Sedation for the maintenance of an established ETT
Contraindications - Fentanyl
KSAR or hypersensitivity to fentanyl
NAS administration:
- GCS < 14
- suspected nasal or mid fractures
- blood or mucous obstructing the nasal passage
Precautions - Fentanyl
Elderly patients Hypotension Respiratory tract burns Respiratory depression and/or failure Known addiction to narcotics Patients taking monoamine oxidase inhibitors (MAOIs)
Side effects - Fentanyl
Bradycardia Drowsiness Hypotension Nausea and/or vomiting Pin point pupils Respiratory depression Muscular rigidity (particularly muscles of respiration)
Fentanyl Adult dosages - Significant Pain
IM 25–100mcg (ICP)
Repeated at up to 50 mcg every 10 minutes No maximum dose
IV/IO 25–50mcg (ICP)
Repeated at up to 50 mcg every 5 minutes
No maximum dose
NAS 1.5 mcg/kg
Repeated once at 1 mcg/kg after 10 minutes
Fentanyl adult dosage - Sedation for the maintenance of an established ETT
IV/IO 25 mcg (ICP)
Consider administration with midazolam. Repeated PRN
No maximum dose
Fentanyl Paediatric dosages
Significant pain
NAS > 1 year – 1.5 mcg/kg
Repeated once at 1 mcg/kg at 10 minutes.
Total maximum dose 100 mcg
< 1 year – SJANT on-call medical officer consult and approval required in all situations
Indications - frusemide
Congestive cardiac failure
Fluid overload
Oliguria (after correction of hypotension and hypovolamia)
Contraindications - frusemide
KSAR
Patients < 12 years of age
Precautions - frusemide.
Hypotension
Side effects - frusemide
Marked diuresis can lead to hypotension
Potassium loss associated with diuresis may aggravate or potentiate dysrrhythmias
Adult dosages - frusemide
Congestive cardiac failure
Fluid overload
Oliguria
after correction of hypotension and hypovolaemia
IV 40 mg (ICP)
Consider repeating after 5 minutes.
Maximum total dose 80 mg
Indications - Gastrolyte
Oral correction of fluid and electrolyte loss
Contraindications - Gastrolyte
Not be administered to infants <2 year
Intestinal obstruction
Precautions - Gastrolyte
Only mixed with water
Side effects - Gastrolyte
Nil
Adult dosages Gastrolyte
Symptomatic dehydration (with the ability to self administer)
PO 1 sachet
Re-constituted with 200 ml water
May repeat PRN
Gastrolyte paediatric dosage
PO 1 sachet
Re-constituted with 200 ml water
May repeat PRN
Indications - Glucagon
Symptomatic hypoglycaemia (with the inability to self- administer oral glucose)
Contraindications - Glucagon
KSAR
Precautions - Glucagon
Nil
Side effects - Glucagon
Nil
Adult dosages - Glucagon
Symptomatic hypoglycaemia
with the inability to self administer oral glucose
IM 1mg
Single dose only
Glucagon Paediatric dosages
Symptomatic hypoglycaemia
with the inability to self administer oral glucose
IM
>25Kg -1mg Single dose only
< 25 Kg – 500 mcg Single dose only
Indications - Glucose 5%
As a vehicle for drug delivery during IV drug infusion administration.
Contraindications - Glucose 5%
Nil
Precautions - Glucose 5%
Hyperglycaemia
Side effects - Glucose 5%
Nil
Glucose 5% Adult dosages
As a vehicle for drug delivery during IV drug infusion administration
IV INF
As documented on DTP
Maximum Dosage 1000ml
Glucose 5% Paediatric dosages
As a vehicle for drug delivery during IV drug infusion administration
IV INF (ICP) As documented on DTP
Maximum Dosage 500ml
Indications - Glucose 10%
Symptomatic hypoglycaemia (with the inability to self- administer oral glucose)
Contraindications - Glucose 10%
Nil
Precautions - Glucose 10%
Tissue and/or vascular necrosis secondary to extravasation.
Side effects - Glucose 10%
Nil
Glucose 10% Adult dosages
Symptomatic hypoglycaemia
with the inability to self administer oral glucose
IV 150 ml
Repeated at 100 mL boluses every 5 minutes until BGL > 4.0 mmol/L
IO 150 mL ( ICP)
Repeated at 100 mL boluses every 5 minutes until BGL > 4.0 mmol/L
Glucose 10% Paediatric dosages
Symptomatic hypoglycaemia
with the inability to self administer oral glucose
IV 2.5 mL/kg (ICP)
Repeated at 1 mL/kg boluses every 5 minutes
until BGL > 4.0 mmol/L
IO 2.5 mL/kg (ICP)
Repeated at 1 mL/kg boluses every 5 minutes until BGL > 4.0 mmol/L
Indications - Glucose gel
Symptomatic hypoglycaemia (with the ability to ingest oral glucose)
Contra indications - Glucose gel
KSAR
Unconsciousness
Patients with difficulty swallowing
Patients < 2 years
Precautions - Glucose gel
Nil