Protien synthesis: Mutations Flashcards
Base substitution mutation
Is a form of mutation where a single nucleotide base is replaced or substituted with another.
Same-sense
The substituted base does not cause a change in the amino acid sequence
Missense
causes a change in the amino acid sequence, but does not cause a change in the shape or function of the protein.
Nonsense
Substituted base results in the production of a stop codon, has a severe impact on the protein formed.
Single base insertion
A form of DNA mutation where one base is added into the DNA chain, changing the genetic code dramatically.
Single base deletion
A form of DNA mutation where one base is removed from the DNA chain, and lost forever.
Reading frame-shift
a genetic mutation caused by a deletion or insertion of a base in a DNA sequence that shifts the way the sequence is read (in triplets).