Proteinuria Flashcards
1
Q
Normal urinary protein excretion per day?
A
normal = 80 mg/day
and <150
albumin 15% of this
2
Q
what is benign proteinuria?
A
<1000mg /24 hours in children
3
Q
transient causes of proteinuria?
A
fever
exercise
UTI
4
Q
generall aetiology of proteinuria?
A
glomerular - 1-20g per day, generally albumin & haematuria, caused by DM, HTN, minimal change, FSGS, SLE, IgA, amyloid
Tubular - 2g per day, LMW proteins generally, ATN, interstitial, obstruction, cystic
overflow - myeloma, rhabdo, polymyositis
5
Q
problems with using dipstick to investigate proteinuria?
A
dipstick testing limited sensitivity for non-albumin proteinuira
- falsely negative in tubular/overflow proteinuria
6
Q
Ix if dipstick finds proteinuria?
A
24-hour collection
urine ACR on morning sample
urine PCR
MSU
bloods U&E ESR IG Abs electrophoresis
