Proteins And Mutations Flashcards
Insulin
Hormone that helps control blood sugar levels
Haemoglobin
Is a carrier protein
found in red blood cells
binds with oxygen
Collogen
Structural protein found in connective tissue
Enzymes
Proteins that act as biological catalysts
Enzymes are highly specific and speed up particular chemical reactions eg, respiration
What explain factors will affect the rate of enzyme activity and what happens
Temperature- Increases collisions between reactants and enzymes. Too high and enzymes denature, too low and reaction rate is lowered and enzyme won’t collide as much
pH- optimum pH varies. Too high/low and enzymes become less effective
What are good conditions for human enzymes (temperature)
Body temperature 37 degrees
In an enzyme, explain what allows the substrate to be changed
Active sites temporarily bind to substrate molecules/reactants allowing substrate to be changed
Reactant is broken down and enzyme can be reused
(Lock and key mechanism)
What can happen to enzymes at extreme temperature and pH
What happens
They can become denatured so enzyme activity stops
Bonds in the protein break and shape of the active site is changed irreversibly, enzyme and substrate cannot bind
Lock and key mechanism no longer works
How could mutations be beneficial
The new function could function better
How is mutation frequency increased
Exposure to: UV light Radioactive substances X-rays Chemicals
How could a mutation be caused
If base sequence changes, sequence of amino acids changes
different proteins are produced
This caused the gene to change
This gene can be passed on through mitosis