Proteins Flashcards
what happens when the weak interactions break?
Loss of structure and function
what are the different weak interactions between biomolecules?
Hydrogen bonds
Ionic interactions
Hydrophobic interaction
Van der Waal’s forces
what does the solubility of molecules depend on?
the ability to form H bonds with the water
what are polypeptides?
amino acids covalently joined together
what determines the sequence of amino acids?
the sequence of bases on the gene
what does the folding of polypeptide chains depend on?
the sequence of amino acids
the physical and chemical properties of the amino acids
amino acids can exist as stereoisomers. what type exist in human proteins?
L isomer
how are amino acids classified?
according to the chemical properties of the R groups
what happens to the R group when pH is greater than pK?
R group is deprotonated
what happens to the R group when pK is greater than pH?
R group is protonated
how are peptide bonds formed?
the carboxyl group and the amino group reacts to form the bond, eliminating a water molecule
what type of peptide bond exist in human proteins?
Trans peptide bond - C is on opposite sides of the peptide bond
what is the isoelectric point, pI?
the pH at which there is no overall charge
what happens to the R group when pI is greater than pH?
the R group is protonated
what happens to the R group when pH is greater than pI?
R group is deprotonated
