Proteins Flashcards
What is an amino acid?
A monomer which makes up proteins
What does the shape/function of a protein depend on?
Sequence, type and number of amino acids
How many amino acids are there?
20
What is the general structure of an amino acid?
-Central Carbon
-NH2 amine group on left
-COOH carboxylic group on right
-H on bottom
-R group on top
How are proteins joined?
Peptide bonds
Describe how a peptide bond forms
-Hydroxyl of carboxylic acid and hydrogen of amine group are lost (1 water molecule)
-Remaining carbon and double oxygen, bond to nitrogen of adjacent amino acid
-Water is released
-Condensation reaction
Describe the primary structure of a protein
-Sequence of amino acids
-Peptide bonds
Describe the secondary structure of a protein
-Initial folding of polypeptide chain
-Hydrogen bonding
-Alpha helix or beta pleated sheets
Describe the tertiary structure of a protein
-Overall 3D shape
-Hydrogen & ionic bonding
Describe the Quaternary structure of a protein
-2+ polypeptide chains stacked to form a single protein molecule
-Hydrogen bonding & disulphide bridges
What is a globular protein?
-Almost spherical
-Soluble
-Metabolic functions
What is a fibrous protein?
-Regular amino acid sequence
-Insoluble
-Structural functions
Describe the structure of elastin
-Fibrous
-Short sequence of 3-9 amino acids
-Flexible
-Recoils after being deformed
-Insoluble
Describe the function of elastin
-Allows tissues in the body to shrink out and back
e.g. Bladder, Lungs
Describe the structure of collagen
-Fibrous
-Triple helix
-Flexible
-No stretch
-Insoluble