Proteins Flashcards
Building blocks of proteins
Amino Acids
Enumerate the parts of the general structure of Amino Acids
Amino Group Carboxyl Group Tetrahedral Alpha Carbon Hydrogen Variable Side Chain
What is the purpose of the variable side chain in the structure of Amino Acids?
Determines the identity of the Amino Acid
Ways to depict amino acids structure. Rules of each.
Geometric Formula/ Stereochemical Rendering (Solid, in front, dashed, at the back) Fischer Projection (Vertical lines, away, horizontal, toward)
Nonsuperimposable images of amino acids
Enantiomers
Clockwise rotation of groups in amino acids based on prioritization of the Cahn-Ingold-Prelog System, in the optical activity that rotates incident light.
Dextrorotatory
Counter-Clockwise rotation of groups in amino acids based on prioritization of the Cahn-Ingold-Prelog System, in the optical activity that rotates incident light.
Levorotatory
Cahn-Ingold-Prelog System
assigns priorities to groups based on atomic number
R rectus right
S sinistrus left
Rosanoff/Fischer Projection based on glyceraldehyde
D/L
Important in protein folding
Hydrophobic
R group with electronegative atom that can form H bonds with water
Pola, uncharged
negatively charges amino acids describe
carboxyl group in R group, negative net charge at physiological pH, acidic
positive net charge at physiological ph, basic
Positively charged amino acids