Protein Synthesis - Transcription Flashcards

1
Q

what is transcription

A

info encoded in DNA copied into complementary RNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Promotor

A

sequence that lies just before a gene

serves as a signaling sequence, marking the starting point and direction for RNA polymerase to begin transcribing a gene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Promotor in Eukaryotes

A

TATA box –> hydrogen bonds are easier to break

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Promotor in Prokaryotes

A

TATAAT sequence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is enlongation

A

RNA polymerase makes a complimentary copy in the 5’–> 3’, using the 3’ to 5’ as template

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Examples of termination

A

Termination code
in Prokaryotes - bind to mRNA + stop it
mRNA binds with itself

RNA poly binds to another promotor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Post-transcriptional modifications

A

Poly A Tail

5’ Cap of 7 guanine

cut introns using snRNPs + mRNA (complex if spliceosome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is alternative splicing

A

cells can choose different combinations of exons from the same pre-mRNA to make a final mRNA –> why humans can produce 100 000 proteins from 20 000 genes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly