Protein Structure Flashcards
Protein starts to fold into shape once it’s _____.
Synthesized
Primary structure
Unique sequence of amino acids held together by peptide bonds, determined by gene sequence
Secondary
Repeated coils and folds in polypeptides, helices or sheets, come together by hydrogen bonding
Tertiary
2 or more secondary structures held together by interactions between side chains
Quaternary
Multiple folded polypeptides in association with one another
Globular
Eg. Hemoglobin (2 alpha and 2 beta chains)
Fibrous
Eg. Collagen 3 polypeptides coiled
Protein structure is affected by: (4)
pH
Solvent
Solute concentration
Temperature
How can ph temp solvent and solute concentration affect protein structure
Disrupts forces holding different levels of structure together
Protein is ______ when it has lost proper 3D structure and _____ functions
Denature, loses
Chaperonin
Assist the proper folding/refolding of other proteins