Protein Sorting/ Targeting Flashcards
1
Q
Protein destinations and if after or during translation (3)
A
Stay in cytosol
Mitochondria + nucleus - Post translational
Secretory pathway - Co-translational trafficking
2
Q
What determines sorting of protein in secretory pathway
A
Signal sequences
3
Q
What directions are proteins made
A
N-terminus to C-terminus (5’ to 3’ direction)
4
Q
Overview steps of post-translation (4)
A
stay in cytosol
Protein synthesis on free ribosomes
proteins folded
Transported to nucleus, mitochondria, chloroplast, peroxisomes
5
Q
In post translation: how is the protein sorted to the nucleus
A
Uses Nuclear
