Protein metabolism (1.6)

Question 1

How is pepsin formed?

Answer 1

Pepsinogen is secreted into the acidic lumen

Question 2

What enzyme activates trypsinogen to trypsin?

Answer 2

Enteropeptidase

Question 3

What proteases does trypsin activate?

Answer 3

Chymotrypsin (from chymotrypsinogen)
Elastase (from proelastase)
Carboxypeptidase (from procarboxypeptidase)

Question 4

how are tri/di-peptides and amino acids transported into the intestinal epithelial cells?

Answer 4

Co-transported with Na+

Question 5

What does the mTORC1 complex do?

Answer 5

Activates protein synthesis

Inhibits autophagy

Question 6

When would the mTORC1 complex be active?

Answer 6

During a positive metabolic state

Question 7

What do TSC1 and TSC2 do?

Answer 7

Inhibit mTORC1 complex

Question 8

What activates TSC1 and TSC2?

Answer 8

AMPK

Question 9

When would AMPK activate TSC1 and TSC2?

Answer 9

During a negative metabolic state

Question 10

What is the recommended protein intake of a 0-6 month old?

Answer 10

60g

Question 11

What is the recommended protein intake of a 6-9 month old?

Answer 11

95g

Question 12

What is the recommended protein intake for people greater than 1?

Answer 12

0.8g/kg