protein introduction Flashcards
what are proteins?
proteins are a chain of amino acids that have a variety of functions reflected by the wide structural properties of
name some functions of a protein
-Recognition of specific molecules including hormones, antibodies and DNA binding proteins
-Movement of other molecules like porins which sit on the outer membrane of bacteria that allows diffusion
-structural functions like the cytoskeleton which holds everything together in the cell
- Enzymes which speed up a rate of a chemical reaction
what are proteins joined into?
polypeptide chains
what are short chain proteins called?
peptides
(less than 50 amino acids)
what are native/ folded proteins
The final folded form which is a thermodynamically stable
Define a secondary protein structure
Regular repeating structures which are stabilised by hydrogen bonds
what is an alpha helix structure?
hydrogen bonds between amino (+) and carboxyl (-) groups of amino acids 4 residues apart
What is a beta sheet structure
Hydrogen bonds between amino and carboxyl group of amino acids further away from each other in the primary sequence on different strands
what is a quaternary protein structure?
when polypeptides come together to form a more complex structure with two or more subunits
what is phosphorylation
Reversible addition of phosphate (PO3) group by enzymes called kinases.
This is an important way of regulating enzyme function.