protein contol of cell division Flashcards

1
Q

anaphase

A

phase in which spindle microtubules shortend by depolymerisation sister chromatids are seperated and the chromosomes are pulled to opposite poles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

apoptosis

A

programmed cell deathc triggered by interanal or exteranal signals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

caspase cascadee

A

protease enzymes involed in a series of reactions that destroy a cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

cell cycle

A

cell increases in size- G1
copies DNA- S stage
preps to divide- G2
and divides my mitosis-Mstage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

cell cycle checkpoints

A

G1,2 and Metaphase checkpoints assesse the rediness of a cell to enter the next stage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

centromere

A

the specialised DNA sequence of a chromosome that links to a pair of sister chromatids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

cyclin proteins

A

proteins that control the progression of cells throughout the cell cycle by activatiing CDK enzymes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

CDKS

A

when activated by cyclin it causes the phosphorylation of protiens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

cytokinesis

A

divison of cytoplams to form two daughther cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

cytoskeleton

A

supports cells shape and function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

death signal molecules

A

activates caspase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

G1 cyclin-CDK

A

phosphoriylating by G1 cyclin-CDK inhibits the Rb allowing the transcription of the genes that code for proteins needed for DNA replication

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

interphase

A

phase of the cell cycle contains G1,2 and S phases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Kinetochores

A

where microtubles of the spindle attach

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

metamorphosis

A

process the involves a significant change in an organisms physical form

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

metaphase

A

phase when chromosomes align at the metaphase plate and attach to the spindle fibers

17
Q

MTOC

A

structure in eukaryotic cells from which microtubles are produced for the formation of spindle fiberes

18
Q

microtubles

A

hollow tubes made up of tubulin

19
Q

mitosis

A

division of the nucleus to form two new nuclei

20
Q

p53

A

a tumour suppressor protein that can stimulate DNA repair

21
Q

prophase

A

a phase where DNA condenses into chromosomes each consisting of two sister chromotids
the nuclear membrane breaks down the spindle forms and chromeosomes attach via their kinetochores

22
Q

proto-oncogene

A

a normal gene involved in cell growth or division

23
Q

Rb

A

a tumour suppressor protein

24
Q

spindle fibers

A

microtubels to which chromomosomes are attached by kinechores

25
telophase
chromosomes decondense and nuclear membranes are formed around
26
tubulin
protein that polymerises into long chains or filaments that form microtublues
27
tumour promoting oncogene
a mutated proto-oncogene gene that has the potentioal to casue cancer