Proteiin

Question 1

Name the first and last end of polypeptide chain

Answer 1

Free amino group- N terminal - first a.a
Free carboxyl group- C terminal- Last a.a

Question 2

Name the two polypeptide chains of insulin

Answer 2

A chain- Glycine chain-21a.a
B chain- phenylalanine- 30 a.a

Question 3

Human insulin is structurally similar to?

Answer 3

Porcine insulin

Question 4

Human insulin is structurally similar to?

Answer 4

Porcine insulin

Question 5

What is proinsulin?

Answer 5

Proinsulin is a single polypeptide chain with 86 a.a .

Question 6

How is biologically active insulin formed?

Answer 6

By removal of central portion of pro-insulin before release.C-peptide is also released into circulation

Question 7

Which structure of protein determines its biological activity?

Answer 7

Primary structure

Question 8

Sicle cell anaemia

Answer 8

6th position of beta globin chain is valine instead of glutamic acid

Question 9

Give example of alpha helix structure

Answer 9

Hemoglobin and myoglobin

Question 10

Example of globular protein& Fibrous protein

Answer 10

Globular :- Albumin,Globulin,protamines
Fibrous:- Collagen,Elastin and keratins

Question 11

Give example of oxidoreductase

Answer 11

Lactate Dehydrogenase (NAD);Glucose-6-phosphate dehydrogenase(NADP);Succinate dehydrogenase(FAD) ;Dioxygenases

Question 12

Give example of transferase

Answer 12

Transferase transfers group other than H+
Aminotransferase

Question 13

Classification of enzyme

Answer 13

Oxidoreductase,Transferase ,Hydrolase,Lyase,Isomerase,Ligase