Protecting groups Flashcards

1
Q

protecting grp for aldehydes and ketones and how to deprotect

A

acetals and deprotect using hydrolysis, H2O & H+

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2
Q

PROTECTING GROUP FOR ALC AND HOW TO DEPROTECT

A

protected using TERTBUTYLDIMETHYLSILYL (TBDMS) and deprotected using TBAF (Tetra-n-butylammonium fluoride)

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3
Q

PROTECTING GROUP FOR Amines AND HOW TO DEPROTECT

A

carbamates e.g. BOC- TERTBUTOXYCARBONYL GROUP and deprotected using TFA- TETRAFLUOROACETICACID

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4
Q

PROTECTING GROUP FOR CARBOXYLIC ACIDS AND HOW TO DEPROTECT

A

ESTERS

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