Prostate cancer

Question 1

associations

Answer 1

FH, incr testosterone

Question 2

what type are most of the cancers

Answer 2

adenocarcinomas arising in peripheral prostate

Question 3

how can it spread

Answer 3

local (seminal vesicles, bladder, rectum); via lymph; or haematogenously (sclerotic bony lesions)

Question 4

symptoms

Answer 4

asymptomatic or nocturia, hesitancy, poor stream, terminal dribbling or obstruction, weight loss and bone pain suggest mets,

Question 5

diagnosis

Answer 5

incr PSA, transrectal USS and biopsy, X rays, bone scan, CT/MRI

Question 6

staging

Answer 6

MRI

Question 7

treatment

Answer 7

disease confined to prostate- radical prostatectomy, radical radiotherapy, hormone therapy. metastatic disease- hormonal drugs, chemo , treat hypercalcaemia