prostate Flashcards
normal weight of prostate
20g
prostate capsule and relation to peritoneum
no distinct capsule and retroperitoneum
4 zones of prostate
central, peripheral, transitional and periurethral
importance of zones in prostate
hyperplasia occurs in transitional zone
ca occurs in peripheral zone
two layers
basal is low cuboidal cells
then columnar secretory cells facing center
4 types of prostatitis
acute bacterial
chronic bacterial (WBC and bug)
chronic non-bacterial (WBCand no bug)
granulomatous
another name for BPH
nodular hyperplasia
main androgen of the prostate
dihydro testosterone (DHT)
what makes DHT
stromal cells in the prostate
what causes BPH
lack of cell death presumably (not proliferation)
two growth factors in BPH
fibroblast GF and TGF beta
two stains for prostate basal cells
p63
CK903 (HMWCK)
absence of this layer means cancer
PIN4 stain contents
3 components
AMACR (Racemase)
p63
HMWCK (CK903)
ASAP is an indication for
rebiopsy
atypical small acinar proliferation
normal prostate should look like
regularly irregular
