Prosopagnosia Flashcards
DeHann, Young & Newcombe, 1987
Patient PH: associative prosopagnosia. Could match to FRU but not PIN
Schweinberger (1998)
Identity can affect expression judgements
Bauer 1984; Tranel & Damasio 1985
PPAs = higher SCRs to familiar faces
Bate 2010
Oxytocin improves face recognition in DPs. Modulates distributed face processing network, particularly the amygdala
Domes 2010
Oxytocin modulates FFA in face emotion processing task
Haxby 2000
OFA = initial visual face processing, FFA = facial identity, STS = changeable aspects e.g. emotion
Delvenne 2004
Associate PPA was actually perceptual
Avidan 2014
DPs = no composite effect
Duchaine 2006
Edward = no face inversion effect
Barton 2009
Apperceptive PPAs: configural deficit (for face stimuli and dot patterns) - although some evidence of whole-object processing
Lobmaier 2010
DPs = disrupted face-specific, configural processing (impaired for blurred faces but not blurred objects or scrambled faces etc)
Van Belle 2010
Acquired PPA = patient PS had abnormal eye gaze exploration patterns so reflects feature-based processing approach
Biotti 2017
Highly significant composite effect in DPs
Yovel & Duchaine 2006
PPAs impaired for both shapes and features and spacing between them
Witthoft 2016
DPs had smaller pRF sizes in ventral face network that rarely extended to ipsilateral or peripheral VF = impaired spatial integration of facial features
Johnston and Morton 1991
Babies innate ability to attend to faces
Farah 1995
Faces = within-category so harder. But not just due to this as created OR task of comparable difficulty and PPAs still worse at faces
Moscovitch 1997
CK: visual agnosia but no PPA
Sergent and Signoret 1992
RM Impaired for faces but not cars
McNeill and Warrington 1993
WJ PPA for human faces but not sheep faces
Duchaine and Yovel 2006
Edward (DP) = impaired at faces but not within-category objects so mechanisms for each = separate developmental processes
Rangarajan 2014
EBS to right FFA only = deficits in conscious face perception e.g. distortion of faces, while left FFA = non-face related aspects e.g. colour changes
Jonas 2014
EBS to right (but not left) OFA = impaired face discrimination
Hadjikhani 2002
PPAs (1 DP, 2 AP) did not show normal increase in FFA or OFA fMRI activation in response to faces (objects and faces had similar activation)
Avidan 2005
DPs showed normal FFA activation (although could be disconnection syndrome? Could be continuum?)
FFA detection only, full recognition requires activation of anterior temporal semantic stores.
But: Grill-Spector 2004. Could be feedback mechanisms?
Dalrymple 2011
No N170 if both OFA and FFA. Spared if only bilateral FFA damaged. Also patient with only STS damage only showed impairment when expression changed. So need at least two components of FP network spared?
Schiltz 2006
Damaged OFA = reduced responses in FFA (feedback)
Barton 2003
Posterior occipital lesions = perceptual deficits (impaired structural and matching to FRUs), anterior temporal = can’t extract semantic info (match to PIN)
Gomez 2015; Song 2015
DPs had abnormal white matter around FFA so disconnection syndrome?
Renzi 2013
Right DLPFC is involved in holistic processing. DPs show higher fMRI activity in this area = compensatory (but ineffective) mechanism?
Cattaneo 2016
Polymorphisms in OXTR associated with DP
Fisher 2017
DPs = attenuated N250 in identity matching task.
Identity-specific deficit.
Johnen 2014
Family of DPs: all showed varying severity of PPA and general visual deficits.
Continuum!
Avidan & Behrmann 2008
DPs better at familiar face matching than unfamiliar.
= covert recognition
Eimer 2012
DPs had intact N250 (occipito-temporal) for non-recognised famous faces, but no P600f.
Suggests disconnection between intact identity-specific memory and later semantic stages, which are necessary for full FR.
Grill-Spector 2004
Differential FFA activation for face detection vs face identification tasks.
Barton 2003
Anterior temporal lesions = worse at task involving extraction of long-term memory representations / mental imagery.
