Propofol Flashcards
state the class/family of drugs that Propofol belongs to
hypnotics or anaesthetics
Is Propofol a trade or generic name
generic
what other name is Propofol known by
Diprivan
is this a trade or generic name
trade
state the half life of Propofol
estimated between 2 to 24 minutes
what schedule of controlled drug is Propofol classified as
schedule IV controlled drug
how would Propofol be stored when not in use
in a controlled drugs cabinet, metal, locked and fixed to the wall, Access by 2 people and sign drugs in and out. Records and documentation to be kept for 2 years
Propofol is available in what presentation
200mgs in 20mls -10mgs per ml
what colour is Propofol
white milky liquid
what information can be found stamped on an ampoule
drug name
concentration
batch number
expiry date
why is Propofol known as the milk of amnesia
because of its milk like appearance
how is Propofol administered on a patient when used for conscious sedation
Propofol is used with a patient-controlled electronic infusion pump driver so that it can be continually administered. the pump driver is set up by the clinicians or the anaesthetist by inputting the amount of drugs a patient will receive each time they press a button and the interval period between activations. This means that the patient is in control, because they hold the button throughout the treatment, which when pressed will administer a dose of Propofol, Due to the date input, they would not receive a dose every time they pressed the button, because of the lock-out time. The initial bolus is approximately 1mg/kg over 1-5minutes followed by 1.5-4.5mg/kg/hour
Propofol causes pain on administration, how can this be overcome
by administrating a local anaesthetic into the vein prior to the induction of Propofol
who can administer Propofol or dental sedation
anaesthetists and clinicians trained in intensive care procedures. it is normally provided in a hospital setting
how does Propofol sedate a patient
it works by enhancing the effect of the GABA to depress the CNA without using the receptors directly
what is the approximate onset action time for Propofol
30-45 seconds
what are the clinical effects of Propofol
produces sedation and can cause unconsciousness. Causes a 30% fall in blood pressure on induction. Apnoea can occur
state 2 contraindications for the use of Propofol
Respiratory depressants such as benzodiazepines, opiates, alcohol, heroin and morphine
state two adverse effects that can occur by using Propofol for dental sedation
it is a respiratory depressant. low blood pressure and apnoa. Pain on administration, mild myoclonic movements (muscle twitches) and euphoria. Some patients can experience profound sedation even with a small dose of Propofol. Patients allergic to eggs =. Pregnant and nursing mothers
how is Propofol metabolised within the body
in the liver
how is Propofol eliminated from the body
in urine from the kidneys
if a patient has presented that they can not take Propofol on their medical history due to an allergy, What would they be allergic to
Eggs
