Properties of Proteins Flashcards

1
Q

What do proteins determine

A
  • nature of species
  • colour of hair, eyes, skin, etc
  • whether a cell is muscle, nerve, epithelial or any other
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2
Q

What does each protein consist of

A

A unique sequence of amino acids and a unique 3D shape

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3
Q

When is the role of proteins important

A

information coded into the molecular structure of DNA.

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4
Q

How are proteins different from other molecules

A

They can bind organic molecules and ions selectively

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5
Q

What is a ligand

A

Any molecule or ion that is bound to the surface of another molecule (protein) by forces other than covalent bonding. e.g. electric attraction

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6
Q

How does a ligand work

A

It binds to specific chemical groups on a small area of the protein surface (binding site). Protein binding depends very much on shape - chemical specificity.

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7
Q

What are the functions of protein binding sites

A
  • Holding cells together
  • Catalysing the chemical reactions in cells (enzymes)
  • Communication between different systems of the body (e.g. hormones)
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8
Q

What is a gene

A

The portion of DNA that contains the information required for transmission

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9
Q

What is a function of DNA

A

The transmission of hereditary information from cell to cell. Contains instructions for the synthesis of proteins coded into its molecular structure.

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10
Q

Describe the characteristics of DNA

A
  • 2 polynucleotide chains coiled around each other to form a double helix
  • 1 molecule of DNA contains the genetic information corresponding to many different proteins arranged as a sequence of genes
  • most of a cell’s DNA is in the nucleus
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11
Q

How is genetic information transferred to protein?

A

1) Code carried from DNA to the ribosome in the cytoplasm by RNA
2) Transfer RNA binds & escorts specific amino acids to the ribosome to place each in the correct order dictated by the triplet sequence in messenger RNA
DNA –> RNA –> PROTEIN

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12
Q

How is genetic information replicated (cell reproduction)

A

For growth of an organism, cells must divide and replicate. Genetic info stored in DNA must be formed and passed onto daughter cells.

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13
Q

What is cell replication generally carried out by?

A

Undifferentiated or stem cells

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14
Q

What is mutation

A

Mistakes in the replications of DNA

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15
Q

How can mutations be advantageous?

A
  • Evolution of living organisms
  • Basis of natural selection
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16
Q

How can mutations be disadvantageous?

A
  • Less effective function
  • Death of the cell by carrying the mutant gene
17
Q

What are the 3 periods that occur during the division of any reproductively active cell?

A
  • Interphase
  • Mitosis
  • Cytokinesis
18
Q

Describe the interphase period

A
  • Longest phase & is the time between cell division
  • The phase where major bodily functions are carried out
  • Most cells are in the interphase state
19
Q

How many long chromatin threads does the interphase nucleus contain

A

46 (half from male and half female)

20
Q

What is mitosis?

A

The process of separating the 46 chromatin threads in each cell nucleus, to produce 2 identical sets of chromosomes in two separate nuclei.
- Provides the daughter cells with an identical set of DNA molecules

21
Q

What is Cytokinesis?

A

The process in which the cytoplasm of a single cell is divided to form two daughter cells

22
Q

What are the 4 types of cell tissues?

A

Epithelial, connective, muscular, nervous

23
Q

What is epithelial tissue for?

A

Protection, absorption, secretion, extretion

24
Q

What is connective tissue for?

A

support, packing material, defence

25
Q

What is muscular tissue for?

A

voluntary, involuntary, cardiac

26
Q

What is nervous tissue for?

A

Conductive, Support

27
Q

What is cell growth generally a result of?

A

1) Hyperplasia - increase number of cells
2) Hypertrophy - increase size of cell

28
Q

What does cancer result in?

A

Abnormal growth of cells. Arises when a cell doesn’t respond to the normal control mechanism and undergoes unlimited growth. Primary mechanism is hyperplasia and forms a tumour.

29
Q

Define metabolism

A

All the chemical reactions occurring in living matter.

30
Q

What law do all chemical reactions obey

A

Law of Conservation of energy

31
Q

Where does the energy come from to produce a chemical reaction?

A

Intrinsic heat (body heat)
Catabolism of carbohydrates, lipids etc.

32
Q

How does the Law of Conservation of Energy relate to chemical reactions in the body?

A

The difference in energy content between reactant and product molecules must equal the amount of energy added or released during the reaction
Release chemical energy appears mainly in the form of heat
Joules (calories)

33
Q

What is the function of ATP

A

transfer the energy released from the breakdown of carbohydrates etc. to the many different energy-requiring processes in the cell

34
Q

Describe ATP

A

Made up of 1 ADENOSINE molecule and 3 PHOSPHATE molecules. Held together by high energy phosphate bonds. The energy stored in the phosphate bonds is what is released to cause muscular contractions.

35
Q

What happens as a result of the catabolism of glucose to CO2 and H20

A

Energy is released
Achieved by Glycolysis and the Krebs cycle

36
Q

Where are the things that aren’t catabolised stored?

A
  • Liver
  • Muscle
  • Synthesis of fat
37
Q

What is Glycolysis

A

Glycolysis is the breakdown of Carbohydrates (in the form of Glucose or Glycogen) into Pyruvic acid and two ATP molecules.

38
Q

Describe Carbohydrate catabolism

A

Food =carbohydrate & protein&raquo_space; carbohydrate&raquo_space;
- CATABOLISM&raquo_space; ATP + CO2 + H20
- ANABOLISM&raquo_space; glycogen/ fat

39
Q

Describe Fat catabolism

A

Food= fat & protein & carbohydrate&raquo_space; fat
fat&raquo_space; fatty acids & glycerol&raquo_space; acetyl coenzyme A&raquo_space; Krebs cycle (CO2) & coenzyme (2H)&raquo_space; Oxidative phosphorylation (O2 & H20)&raquo_space; ATP