Prolactinoma Flashcards
1
Q
What is the definition?
A
A benign lactotroph adenoma that secretes prolactin
2
Q
What is the aetiology?
A
- Prolactin-secreting pituitary adenomas
- Most occur sporadically
- Genetic causes (5% of cases)
- MEN-1
- carney complex
- familial isolated pituitary adenoma syndrome
3
Q
Risk factors
A
- Female gender
4
Q
Pathophysiology
A
Pituitary size:
- microadenomas ≤ 10mm
- Macroadenomas > 10mm
with suprasellar extension may result in bitemporal hemianopia.
Functional pituitary adenoma (60%)
- secretory pituitary adenomas
- associated with hormone secretion and therefore hyperpituitarism
- commonly one hormone secretion
- prolactinoma is associated with excessive
