proficiency exam Flashcards
vancomycin pharm class____
glycopeptide
vancomycin use___
c Dif, endocarditis, enterocolitis, staphyloccal, streptococcal
vancomycin adverse effects__
hypokalemia, abdominal pain, nausea, nephrotoxicity
vancomycin monitoring parameters___
renal function tests, CBC
vancomycin MOA___
inhibits bacterial cell wall synthesis by blocking glycopeptide polymerization
famotidine pharm class___
histamine H2 antagonist
famotidine use ___
GERD, heartburn, aspiration prophylaxis, stress ulcer prophylaxis
famotidine AE____
agitation
famotidine MP____
CBC, gastric pH, occult blood
famotidine MOA___
inhibition of histamine at H2 receptors of the gastric parietal cells, which inhibits gastric acid secretion
prednisolone pharm class__
adrenal corticosteroid
prednisolone use___
anti-inflammatory, immunosuppressant
prednisolone AE___
osteoporosis (fracture)
prednisolone MP___
BP, wt, electrolytes, glucose, intraocular pressure, suppresses immune system
prednisolone MOA___
decreases inflammation by suppression of migration of polymorphonuclear leukocytes; reducing activity & volume of lymphatic system
piperacillin & tazobactam pharm class___
antibiotic, penicillin
piperacillin & tazobactam use___
intraabdominal/pelvic/skin infections, pneumonia.
bite wound/bloodstream/UT infection, cystic fibrosis, septic shock
piperacillin & tazobactam AE___
diarrhea
piperacillin & tazobactam MP___
creatinine, BUN, CBC w/differential, PT PTT, electrolytes, LFTs, urinalysis, bleeding, anaphylaxis, CNS
piperacillin & tazobactam MOA___
inhibits cell wall synthesis
pancrelipase pharm class___
enzyme
pancrelipase use___
pancreatic insufficiency (exocrine), occluded enteral feeding tubes
pancrelipase AE___
h/a, abdominal pain, lymphadenopathy, streptococcal infection, neck pain, otalgia, nasal congestion
pancrelipase MP___
abdominal symptoms, nutritional, wt, growth (in children), stool character, fecal fat
pancrelipase MOA___
natural product harvested from porcine pancreatic glands dissolve in more basic pH of the duodenum so they may act locally
nystatin pharm class___
anti fungal agent
nystatin use___
(oral) candidiasis
(topical) candida species
peritoneal dialysis-associated infection
nystatin AE___
diarrhea, nausea, stomach pain, vomiting
nystatin MOA___
binds to sterols in fungal cell membrane, changing the cell wall permeability allowing for leakage of cellular contents
morphine pharm class___
opioid analgesic
morphine use___
pain management
critically ill (analgesia/sedation)
dyspnea
morphine AE___
constipation, respiratory depression
pruritus-itchy skin
morphine MP___
pain control, respiratory/mental status, BP, signs of misuse or abuse, addiction, s/s hypogonadism or hypoadrenalism
morphine MOA___
binds to opioid receptors in CNS
montelukast pharm class___
leukotriene receptor antagonist
montelukast use___
allergic rhinitis, asthma (maintenance), exercise-induced bronchoconstriction,
-aspirin-exacerbated respiratory disease, hypersensitivity reaction
montelukast AE___
nervous system disorders, psychiatric/sleep disturbances
montelukast MP___
neuropsychiatric events, suicidal thinking/behavior
montelukast MOA___
selective leukotriene receptor antagonist that inhibits the cysteinyl leukotriene receptor
midazolam pc___
Antiseizure Agent, Benzodiazepine
midazolam use___
General anesthesia, Mechanically ventilated patients in the ICU, sedation, Procedural sedation, outside the operating room, Seizures, intermittent, Status epilepticus: Seizalam
midazolam AE___
Vomiting, apnea, bradypnea, decreased tidal volume, nasal discomfort
midazolam MP___
level of sedation, RR, HR, PB, O2 sat, s/s resp depression
midazolam MOA___
Binds to stereospecific benzodiazepine receptors on the postsynaptic GABA neuron at several sites within the central nervous system, including the limbic system and reticular formation
mesalamine PC___
5-Aminosalicylic Acid Derivate
mesalamine USE___
Oral ulcerative colitis in adults. (remission and active)
mesalamine AE___
abdominal pain, constipation, eructation, h/a, Nasopharyngitis