Prodrug & Active Metabolite Flashcards

1
Q

Capecitabine

A

Fluorouracil

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2
Q

Valacyclovir

A

Acyclovir

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3
Q

Lisdexamfetamine (Vyvanse)

A

Dextroamphetamine

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4
Q

Clopidogrel (Plavix)

A

Active metabolite (CYP2C19 -> active form)
CYP2C19 inhibitors -> omeprazole, esomeprazole

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5
Q

Codeine

A

Morphine (CYP2D6 -> active form)

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6
Q

Cortisone

A

Cortisol

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7
Q

Famciclovir

A

Peniciclovir

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8
Q

Fosphenytoin

A

Phenytoin

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9
Q

Isavuconazonium sulfate

A

Isavuconazole

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10
Q

Levodopa

A

Dopamine

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11
Q

Prednisone

A

Prednisolone

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12
Q

Primidone

A

Phenobarbital

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13
Q

Tramadol

A

Active metabolite

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14
Q

Valganciclovir

A

Ganciclovir

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