Procedures Flashcards
What are the 2 categories of drugs used during a RSI
Induction/Sedation
Muscle Relaxant
What is the most common pre-induction analgaesics used?
- Fentanyl (1-3 microg/kg)
What are the most common drugs used for induction/sedation for RSI?
Propofol (1.5-3mg/kg)
Ketamine (1.5-3mg/kg)
What are the most common paralytic drugs used for RSI?
Rocuronium (1.2mg/kg)
Suxamethonium (1.5mg/kg)
What drugs are most commonly used for analgaesia/tube tolerance?
Fentanyl
Morphine
What drugs are most commonly used for post-intubation sedation?
Propofol
Ketamine
Midazolam
What drug is used for induction-associated hypotension?
Metaraminol (0.5-1mg IV bolus)
What is ketamine? How does it work
- Short acting NMDA antagonist
- Causes dissociation between thalamocortical and limbic systems
- Amnesic, analgesic, sedative, anaesthetic effects
- Minimal respiratory/CVS effects
For ketamine outline:
- Absorption
- Distribution
- Metabolism
- Excretion
Absorption: IV/IM
Distribution: distributed rapidly to all highly perfused tissues incl. brain
Metabolism: extensive hepatic
Excretion: urine
How long does IV ketamine take to onset?
30-60 seconds
How long does IV ketamine provide sedation
10-20 minutes
Outline precautions of the use of ketamine
- Avoid in children <12 months and esp. < 3 months - risk of airway complications
What is propofol? How does it work?
- Non-barbituate
- Short-acting
- Sedative, hypnotic, anaesthetic effects
- CNS depressant
What adverse effects of ketamine?
- Minimal
- Hallucinations
What are the precautions of propofol?
- Hypotensive patients
- Unfasted patients
