Problems Relating to Certain Systemic Conditions Flashcards
What are the components of the surgical sieve?
VITAMIN DIC V - vascular I - inflammatory T - traumatic A - autoimmune M - metabolic I - infection N - neoplastic D - degenerative I - idiopathic C - congenital
Is LA safe to use in pregnancy?
Yes.
The hormonal mechanism shields the uterus from smooth muscle activators.
What is the biggest danger to a foetus in GA?
Anoxia (total depletion of oxygen levels).
Most likely to occur in 3rd trimester as vital capacity of mother’s lungs is decreased and oxygen supply to foetus decreases.
When is the optimum time for a GA in pregnancy
2nd trimester
When is the most common time for spontaneous abortion to occur?
1st trimester
Increased risk of teratogenic drug effects also.
How would you manage a patient with hyperthyroidism?
- OS or use of LA with adrenaline may precipitate thyroid crisis
- Delay surgery until GP gives go ahead.
- GA may be preferable to LA as less upsetting
- Sedation is contraindicated
What are the causes of adrenal insufficiency?
Primary: Addison's - autoimmune breakdown of adrenal glands Secondary: Long term corticosteroids OR Tumour of pituitary - reduces ACTH
What drugs are prescribed for cortisol and aldosterone replacement?
Hydrocortisone
Fludrocortisone
What are the symptoms of adrenal crisis?
Postural hypotension Weakness Vomiting Nausea Fatigue Hypoglycaemia Tachycardia Weak pulse LoC
What are the guidelines for steroid cover with regard to adrenal insufficiency?
NICE Guidelines:
Pts taking 10mg/day prednisolone (or have done in the last 6 months) should be considered.
- Minor dental procedures: no cover
- Medium procedures under LA e.g. RCT: double hydrocortisone dose (up to 20mg) 1 hour before and for 24 hours after
- Major procedures under LA/GA e.g. XTN: 100mg hydrocortisone IM just before surgery, double dose for 24 hours after
How is the immediate management in adrenal crisis?
Crisis = BP below 25% of diastolic
100mg hydrocortisone (IV or IM) alongside saline drip
Adult: 100mg
Child 6+: 50-100mg
Child 1-5: 50mg
Child <1 year: 25mg
Name 3 complications of diabetes mellitus.
- Diabetic ketoacidosis (Type 1): high blood sugar (really dehydrated) so cell sugar is low and body breaks down ketone bodies instead
- Hyperosmolar hyperglycaemic state (Type 2): not as severe as pts have more insulin. Ketone bodies are not broken down
Tx for above: hospital for IV fluids and electrolytes
- Hyperglycaemia (both types): symptoms - tremor, anxiety, dry mouth, sweating, hunger, confusion, slurring words, convulsion, LoC
Tx: sugar drink/gel
If LoC: 1mg glucagon IM
How would you manage a patient with diabetes?
- LA with adrenaline is SAFE to use
- Offer AM appt if possible, ensuring they’ve had breakfast
- Severe diabetics having longer procedures require GKI (glucose, potassium and insulin infusion)
What are the two types of angioedema?
- Hereditary - exaggerated response to minor trauma shared by family members
- due to lack of C1 esterase inhibitor; no complement cascade initiation
- administration of fresh frozen plasma provides this inhibitor
- spontaneous angioedematous attacks treated with steroids - Non-hereditary - allergic response to food, drugs, emotional responses
- if acute reaction occurs treat for anaphylaxis
What is angina?
Occurs when partial occlusion of vessels due to atherosclerosis