Problems r/t Neurocognitive Disorders Flashcards
* Alzheimer’s Disease * Vascular neurocognitive disorders * Frontotemporal neurocognitive disorder * Lewy body dementia
Delirium
✣ disturbance in attn & awareness
✣ change in cognition
✣ diff sustaining & shifting attn
✣ extremely distractible
✣ disorganized thinking prevails
✣ rambling speech, irrelevant, pressured, incoherent
✣ disorientation to time & place
✣ emotional instability
✣ hallucinations/illusions
✣ sleep-wake cycle dist
✣ fluctuating psychomotor activity
Autonomic manifestations of Delirium
✣ tachycardia
✣ sweating
✣ flushed face
✣ dilated pupils
✣ elevated BP
Predisposing Factors of Delirium
✣ Systemic infections
✣ Hepatic or renal failure
✣ Febrile illness
✣ Head trauma
✣ Metabolic disorders, like fluid & electrolyte imbalances, hypercarbia, or hypoglycemia
✣ Seizures
✣ Hypoxia & COPD
✣ Migraine ha’s
✣ Brain abscess or brain neoplasm
✣ Nutritional deficiency
✣ Uncontrolled pain
✣ Burns
✣ Stroke/heat stroke
✣ Orthopedic & cardiac surgeries
✣ Social isolation
Other Etiological Implications of Delirium
- Substance Intoxication Delirium & Substance Withdrawal Delirium
> e.g., alcohol, cannabis, cocaine, inhalants, sedatives, anxiolytics, opioids, hypnotics
Medication-Induced Delirium
> e.g., antihypertensives, anticholinergics, steroids, anticonvulsants, analgesics, anesthetics
- Delirium d/t another medical condition or to multiple etiologies
Neurocognitive Disorder (NCD)
- Impairment in the cognitive functions of thinking, reasoning, memory, learning, & speaking
- Mild or major
- Mild NCD - mild cognitive impairment
- Major NCD - can be reversible or progressive
Neurocognitive Disorder (NCD)
✩ Primary: Alzheimer’s disease (AD) [most common]
✩ Secondary: c/b or r/t another dz or cond (e.g., HIV, cerebral trauma)
Reversible NCD: Temporary (temporary dementia)
- Stroke
- Depression
- S/e of rx’s
- Nutritional deficiencies
- Metabolic disorders
NCD Impairment
! abstract thinking, judgement, & impulse control
! social conduct
! behavior
! personal appearance & hygiene neglected
! possibly lang effects (aphasia)
! personality change
! mood changes
! ability to perform ADL’s, work
In most clients, NCD runs a progressive, irreversible course
?
Is the inability to carry out motor activities despite intact motor function
Apraxia
Stages of Alzheimer’s Disease
Stage 1
No apparent symptoms
Stage 2
Forgetfulness
Stage 3
Mild cognitive decline/disorder
Stage 4
Mild-to-moderate cognitive decline
e.g., confabulation occurs
Stage 5
Moderate cognitive decline
Stage 6
Moderate-to-severe cognitive decline
e.g., can become incontinent w/urine and/or feces
Stage 7
Severe cognitive decline
e.g., bedfast, aphasic
Predisposing Factors of NCD’s: Categories
✶ NCD d/t Alzheimer’s dz
✶ Vascular NCD
✶ Frontotemporal NCD
✶ NCD d/t TBI
✶ NCD d/t Lewy Body dementia
✶ NCD d/t Parkinson’s dz
✶ NCD d/t HIV infection
✶ Substance-induced NCD
✶ NCD d/t Huntington’s dz
✶ NCD d/t prion dz
✶ NCD d/t another medical condition
✶ NCD d/t multiple etiologies
✶ Unspec NCD
NCD d/t Alzheimer’s dz
- Onset is slow & insidious
- Progressive & deteriorating
- Memory impairment, behavioral changes
- Mult factors influence development
Possible causative factors:
- Neurotransmitter alterations (e.g., acetylcholine)
- Plaques & tangles (that lead to neuron death)
- Head trauma
- Genetic factors (e.g., familial pattern)
Vascular NCD
- Significant cerebrovascular dz
- More abrupt onset than in AD, course is more variable
Directly r/t an interruption of blood flow to the brain
- HTN
- Cerebral emboli
- Cerebral thrombosis
Frontotemporal NCD
- Occurs as a result of shrinking of the frontal & temporal anterior lobes of the brain
- Prev called Pick’s dz
- Exact cause is unknown but genetics appears to be a factor
NCD d/t TBI
- Amnesia is the most common neurobehavioral sx following head trauma
- Repeated head trauma can result in dementia pugilistica
- Synd characterized by emotional lability, dysarthria, ataxia, & impulsivity