Problem Set Review Flashcards
1
Q
Microtubules are composed of what protein?
A
tubulin
2
Q
Growing microtubules have what cap at the plus end?
A
GTP-tubulin
3
Q
Loss of the GTP-tubulin at the plus end of a microtubule results in:
A
catastrophe (rapid shrinking)
4
Q
Where is the minus end of growing microtubules located?
A
- the centrosome
- stabilized by the gamma-tubulin ring complex
5
Q
What filaments are major determinants of cell shape?
A
Microtubules and intermediate filaments
6
Q
What domain of kinesics allow binding to specific cargos and targets?
A
variable tail domain
7
Q
What domain of kinesins is highly conserved?
A
motor domain
8
Q
What two molecular motors are related to one another?
A
kinesin and myosin
9
Q
Molecular motors generate energy for mechanical work via:
A
ATP hydrolysis
They are ATPases.
10
Q
The “power stroke” occurs when:
A
the products of hydrolysis are released.
