Prions Flashcards
1
Q
How common is prions?
A
Rare
2
Q
What type of disease is prions
A
Fatal neurodegenerative disease
3
Q
What is prions caused by?
A
A self-propagating infectious protein
4
Q
Prions is resistant to
A
Detergent
Disinfectant
UV
Heat
5
Q
4 types of Creutz-felt Jacob disease
A
Sporadic/classic
Familial/genetic
Variant
Latrogenic
6
Q
What percent of disease is sporadic/classic?
A
90%
7
Q
What percent of the disease is familial/genetic?
A
10%
8
Q
Variant is caused by
A
BSE
9
Q
Latrogenic CJD
A
Blood
Surgical tools
Tissue
10
Q
Kuru is acquired from what behavior
A
Ritual cannibalism
11
Q
Kuru is seen where
A
Fore tribe in Papua New Guinea
12
Q
5 definitive diagnosis of postmortem brain biopsy
A
Neuronal loss Astinocytosis Absence of inflammation Spongiform appearance Accumulation of abnormal prion protein
13
Q
Prion disease is a
A
Transmissible spongiform encephalopathies
