Prions Flashcards

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0
Q

Kuru

A

Transmissible spongiform encephalopathy

Neurological disorder

Related to (CJD)

No known treatment

100% fatal

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1
Q

Creutzfield-Jakob Disease (CJD)

A

Degenerative neurological disorder

Incurable and always fatal

Transmissible spongiform encephalopathy

In cows, called bovine spongiform encephalopathy “Mad Cow Disease”

Can be acquired in humans by a genetic mutation of the prion protein

Promotes misfolding of native proteins destroying function of that protein

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2
Q

Bacteriophage

A

A virus that infects a bacteria

Most common biological entity on earth

The most dense population is found in seawater

Are used as an alternative to antibiotics in part of Europe

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3
Q

Cycles of infection

A
  1. Detection
  2. Attachment
  3. Injection
  4. Synthesis
  5. Arrangement (assemble)
  6. Release
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