Principles of physiology Flashcards

1
Q

What is physiology?

A

the study of the function of living things
- describes how processes occur
-mechanism of action

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2
Q

Define a cell?

A

a basic unit of life

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3
Q

Define Tissue?

A

groups of cells with similar specialisation

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4
Q

What are the 4 types of tissue and function?

A

Epithelial - absorption, protection, secretion
Connective - structural support
Muscle - movement, support
Nervous - communication, coordination, control

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5
Q

Recall the 10 body systems?

A

-nervous
-immune
-reproductive
-circulatory
-respiratory
-musculoskeletal
-integumentary = skin
-urinary
-endocrine
-digestive

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6
Q

Define homeostasis?

A

maintenance of a stable internal environment

In the foundation of physiology, cells make up body systems and functions contribute to homeostasis

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7
Q

Define pathophysiology?

A

abnormal functioning of the body associated with disease

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8
Q

Define Intrinsic?

A

means within/ local, inherent in an organ
e.g. exercising a skeletal muscle - vasodilation of blood vessels

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9
Q

Define Extrinsic?

A

means outside of/ systemic initiated outside an organ to alter its activity
e.g. blood pressure - NS acts on heart and blood vessels

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10
Q

Explain Negative Feedback?

A
  • detects a change away from set point
  • initiates mechanisms to correct situations
  • shuts itself off
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11
Q

What’s the purpose of Negative Feedback?

A

A change in controlled variables triggers a response to oppose it
-> maintains a level of a specific range

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12
Q

Explain Positive Feedback?

A
  • rare within the body - opposes homeostasis
  • control variable continues to move in the direction of the initial change
    -reinforce the change in the same direction > away from the set point
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13
Q

What is the first law of thermodynamics?

A
  • energy can neither be created or destroyed
  • energy input = output
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14
Q

What’s external work and give an example

A

-> energy expended by skeletal muscles
skeletal muscle activity - shivering, posture

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15
Q

What’s internal work and give an example

A

-> all other forms of biological energy expenditure
energy - expending activities required to sustain life - pumping blood

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16
Q

What’s metabolic Rate (MR)

A

-> rate at which energy expended by the body per unit of time
- bodies expenditure eventually appears as heat
- rate of heat production /hr (Kcal/hr)

17
Q

What are the factors that influence MR

A
  • muscular activity
  • shivering
  • food intake
  • anxiety
  • fasting
  • fever
  • hormones - catecholamines, thyroid
18
Q

What is Basal Metabolic Rate (BMR)

A

-> index of metabolism under standardised conditions
-> minimal waking rate of internal energy expenditure

19
Q

What are standardised BMR conditions?

A
  • awake
  • relaxed and rested (>30min)
  • supine
  • warm (20-25)
  • fasting (8hr-12hr)
20
Q

What factors influence BMR?

A
  • Age (increases in children, decreases with age)
  • Gender (increases in males)
  • Genetic determinants
  • Body weight (increase with obesity)
  • Body surface area (taller people it’s higher)
  • Environmental temp
  • Sleep (decreases 10-15%)
  • Hormones -thyroid, catecholamines