Principles antibiotic module 2 (less useful)

Question 1

Describe what is meant by selection pressure and antimicrobial resistance

Answer 1

Question 2

The ability of a bacteria to becomes resistant to an antibiotic is the result of a change in the bacterial DNA, by what 2 mechanisms does this occur ?

Answer 2

1. Genetic mutation - misreading of the DNA
2. Transfer of DNA that codes for antibiotic resistance from one bacterium to another by a) Transformation, b) Conjugation or c) Transduction

Question 3

What are the 3 mechanisms of antibiotic resistance ?

Answer 3

1. Altered antibiotic binding site
2. Destruction or inactivation of the antibiotic
3. Increased efflux