Principles Flashcards

1
Q

What features are common to all eukaryotic cells

A
outer membrane
inner cytosol
cytoskeleton
organelles
inclusions (may / may not be membrane bound)
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2
Q

cytosol

A

solution of proteins electrolytes and carbohydrates

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3
Q

cytoskeleton

A

made from thin intermediate filaments and microtubules

determines shape and fluidity of cell

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4
Q

eukaryotic cell

A

cell with a true nucleus

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5
Q

largest component of cells

A

water- 80%, protein- 15%

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6
Q

type of cell that has most water

A

embryonic cells

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7
Q

Plasmalemma

A

amphipathic phospholipid bilayer (hydrophilic and hydrophobic properties)

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8
Q

what does plasmalemma do?

A

separates cytoplasm from outside environment

material can

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9
Q

5 integral proteins found in plasmalemma

A
receptors
channels
transporters
enzymes
cell attachment proteins
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10
Q

characteristics of cell membrane

A

fluid, changes shape easily, selectively permeable
highly permeable- water, oxygen, small hydrophobic molecules
impermeable- charged ions (sodium)

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11
Q

describe plasmalemma

A

phospholipid bilayer of integral and peripheral proteins with cholesterol embedded

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12
Q

phospholipid

A

polar hydrophilic head (choline, phosphate)

non polar hydrophobic tail (fatty acid chain)

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13
Q

what is the name of a solution of proteins, electrolytes and carbohydrates?

A

inner cytosol

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14
Q

what determines shape and fluidity of the cell?

A

cytoskeleton

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15
Q

what is the name given to other structures within the cytosol which may or may not be membrane bound?

A

inclusions

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16
Q

What is the role of the plasmalemma?

A

separates the cytoplasm from the outside environment

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17
Q

components of plasmalemma

A

bimolecular layer of amphipathic phospholipid molecules with their hydrophilic heads at the outer and inner surfaces. hydrophobic fatty acid chains face towards the middle of the two layers

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18
Q

endocytosis

A

process of capturing a substance from outside of the cell by engulfing it with the cell membrane

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19
Q

exocytosis

A

process of vesicles fusing with plasma membrane and releasing their contents to the outside of the cell

20
Q

what is cell membrane highly permeable to?

A

water, oxygen, small hydrophobic molecules

21
Q

what is cell membrane virtually impermeable to?

A

charged ions ex (Na+)

22
Q

organelle

A

small, intracellular organs with a specific function and structural organisation
ESSENTIAL TO LIFE

23
Q

3 main classes of filaments

A

microfilaments
intermediate filaments
microtubules

24
Q

what are microfilaments composed of?

A

actin

25
Q

which filament is composed of 6 main proteins which vary in cell type?

A

intermediate filaments

26
Q

what are microtubules composed of?

A

alpha and beta tubular subunits

27
Q

what is the special organising centre from which microtubules originate from?

A

Centrosome

28
Q

Stabilising proteins found in microtubules

A

microtubule associated proteins (MAPs)

29
Q

Kinesin

A

ATPase that moves toward cell periphery

30
Q

Dynein

A

ATPase that moves towards cell centre

31
Q

Are microtubules polar or non-polar?

A

Polar

32
Q

where do microtubules polymerise?

A

central portion of the cell then radiate outwards

33
Q

what organelles are found contained in the centrosome?

A

centrioles

34
Q

What are centrioles mainly composed of?

A

specialised microtubule segments

35
Q

what encloses the nucleus?

A

nuclear envelope

36
Q

What is the nuclear envelope composed of?

A
  • inner and outer nuclear membrane

- nuclear pores providing continuity with the cytoplasm

37
Q

what is found between the inner and outer nuclear membrane?

A

perinuclear cistern

38
Q

what is the perinuclear cistern continous with?

A

cistern of the endoplasmic reticulum

39
Q

which of the nuclear membranes is studded with ribosomes and continuous with the rough endoplasmic reticulum?

A

outer nuclear membrane

40
Q

What is the nucleolus?

A

dense area within the nucleus

41
Q

What happens in nucleolus?

A

rRNA is transcribed

Ribosomes are formed

42
Q

What is euchromatin?

A

DNA that is more dispersed and actively undergoes transcription

43
Q

Heterochromatin

A

DNA that is highly condensed and not undergoing transcription

44
Q

What are ribosomes made up of?

A

Small subunits which bind to RNA

Large subunit which catalyses formation of peptide bonds

45
Q

Role of endoplasmic reticulum

A

Form a network of interconnecting membrane bound compartments in the cell

46
Q

2 kinds of endoplasmic reticulim

A

Rough and smooth

47
Q

What is rough endoplasmic reticulum characterised by?

A

Being studded with ribosomes