Principles Flashcards
1
Q
A Robertsonian translocation occurs when…
A
The long arms of two acrocentric chromosomes (i.e., chromosomes with centromeres near their ends) fuse at the centromere and the two short arms are lost.
2
Q
Unbalanced translocations can result in…
A
Miscarriage, stillbirth, and chromosomal imbalance (e.g., Down syndrome, Patau syndrome)
3
Q
A Robertsonian translocation is a balanced chromosomal translocation that commonly involves chromosome pairs…
A
13, 14, 15, 21, 22