Principals Of pharmacology Flashcards

1
Q

What are the factors that alter biovailability ?

A
  1. Drug type
  2. Route
  3. Changes in liver metabolism
  4. GI mucosa
  5. Food abd drugs
  6. Solutability
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2
Q

Metabolism occurs in the liver, kidney, lungs, plasma and intestinal mucosa. A patient with liver desease may get?

A

May get a lower dose of medication

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3
Q

What is additive drug reaction ?

A

Combiane effect of two drugs equal to the same amount od drugs given alone.

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4
Q

Synergysm

A

Drug interation that occurs that produce effect greater that the sum of their separate actions

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5
Q

What route is tuberculing TB administered?

A

Intradermal

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6
Q

How is transdermal apply ?

A

Usually in a patch

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7
Q

Antidepressants work on what way ?

A

Inhibits the reuptake of seratonan

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8
Q

What is a contraindication for MAOI that has to do in the heart ?

A

Hypertension and comgestive heart failure CHF

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9
Q

SSRI medications /antidepressants

A

Citalopram
Fluoxetine
Sertraline
Paroxetine

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10
Q

What is phenytoin for ?

A

Anticonvulsant

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11
Q

What are the benzoa antidepressants

A

Diazepam
Lorazepan
Midazolan
Clonazepam

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12
Q

What class of meds is ondansetron ?

A

Antimetic, nausea meds

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13
Q

Which are the antivertigo meds

A

Meclizine
Diphenhydramine
Benzodiazepines

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14
Q

How does the patient feel after/during ketamine

A

Patient is dissociated from the surrounding

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15
Q

Examplea of local anesthesia

A

Lidocane

Bipivacaine

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16
Q

What is the action salicylates

A

They inhibit prostaglandin

17
Q

What action do NSIDS have ?

A

Inhibits the action of tge enzyme cyclooxyne responsavke for prostaglandin synthesis

18
Q

Antihistamine for allergic reactions and what othee conditions ?

A

Imsobnia, motion sickness and vertigo

19
Q

What is a contraindication fir broncodialators ?

A

Cardiac arrhythmia, narrow glaucoma

20
Q

What are mucolitycs and expectorans and an example of each

A

Antitussives :

Acetylcystine
Guafenesin

21
Q

What are the beta blockers good for ?

A

Hypertension, angina pectoris, tachyarrhythmia and migranes

22
Q

What main symptom would drop whne using diuretica

A

BP goes down

23
Q

Proton pump inhibitora are use for ulcers with ?

A

Hyperpalory

24
Q

Omeprazole is what kind of class that affecta what system ?

A

Proton pump inhibitor from gastrointestinal systems, antacids

25
Q

What decreases intestinal peristalsis which is usually increased in a patient with diarrhea and the medication

A

Anti diarrheals such as loperamide

26
Q

What meds are for diarrhea

A

Loperamide

27
Q

Sulfonylures maybe compromise with what contradition affecting the body

A

sulfonylure is a medication that increases the release of insulin by the pancreas. Infection may change dose requirement

28
Q

What is levothyroxine ?

A

Thyroid treatment

29
Q

Gentamicin, neomycin is what.?

A

Amynoglycoside bactericidal

30
Q

Examples of antivirals

A

Acyclovar
Penciclovir
Oseltamivir

31
Q

What happens if abrut cessasion of corticosteroids ocurred ?

A

Corticosteroida Shuts off he pituitary gland because their high levels, cessation would give adrenal insufficiency can occur

32
Q

How does antimigrane works

A

Acts on intracrenial bloods vesels and sensory nerves, causes vasoconstriction

33
Q

Permetrin are use for ?

A

Scabis

34
Q

Keratolic is a skin disorders meds that treats what? and what medications ?

A

Podofilox 0.5
Salicyde acid 17%

Treats warts, calluses, corns and sebarroheic ketarosis