Primary Prevention Of ASCVD Flashcards

1
Q

List “Life’s Simple 7”

A
  1. BP
  2. Cholesterol
  3. Blood glucose
  4. Get active
    5, Eat better
  5. Lose weight
  6. stop smoking
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2
Q

Leading cause of Cardiovascular disease death?

A

Coronary heart disease

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3
Q

Deaths due to cardiovascular disease in 2020 (globally)?

A

19.1 million

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4
Q

Guidelines on primary prevention of cardiovascular disease?

A

2019 acc/aha Guideline on the primary prevention of Cardiovascular Disease

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5
Q

ASCVD Risk factors? (8)

A
  1. Age/race/ethnicity
  2. Family history
  3. Hypertension
  4. Hyperlipidemia
    5, DM
  5. Tobacco use
  6. Physical inactivity
  7. Obesity
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6
Q

Highest risk by sex & race?

A

Hispanic black women > non-hispanic black men > non-hispanic black women > non-hispanic while or Hispanic women

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7
Q

Guidelines for blood cholesterol?

A

2018 aca/aha blood cholesterol guidelines

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8
Q

How long after smoking cessation for risk of ASCVD to fall to that of nonsmoker?

A

10 years

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9
Q

Nonmodifiable risk factors for ASCVD? (4)

A
  1. Age - women > 55 and men >45
  2. Sex
  3. Family history of premature disease ( age < 55 year in men or >65 year in women). First-degree relative
  4. Ethnicity
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10
Q

Most common way for CV risk to be estimated?

A

Acc/aha pooled cohort equations - 10 year ASCVD Risk.
- For ages 40-75
- High risk = 20%
- intermediate- 7.5 - 19.9%
- borderline = 5% - 7.4%

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11
Q

When should 30-year ASCVD Risk be calculated/ used?

A

Adults aged 20-39

Adults aged 40 - 59 years with 10-year risk less than 7.5%

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12
Q

Risk factors that require additional discussion with patient? ( 9)

A
  1. Premature family history
  2. Primary hypercholesterolemia
  3. Metabolic syndrome
    4.ckd
    5, chronic inflammatory conditions
  4. History of premature menopause.
  5. History of pregnancy- associated conditions that increase CV risk
  6. High risk race/ethnicity
  7. Lipid biomarkers
    - apob > 130
    - lipoprotein (a) >50
    - triglycerides > 175
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13
Q

What additional assessments can be done after initially looking at patient risk? (4)

A
  1. High-sensitivity C-reactive protein
  2. Coronary artery calcium score
  3. Ankle-brachial index
  4. Family history of CV disease
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14
Q

Lifestyle modifications for Lipids? (4)

A
  1. Heart-healthy diet
  2. Regular exercise
  3. Maintain healthy weight
  4. Smoking cessation
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15
Q

USPSTF recommendations for statins?

A
  1. Start statin in age 40-75 with one or more risk factor and 10-year ASCVD Risk 10% or more. Start with moderate intensity
  2. Offer statin for risk 7.5-9.9%
    3, NOT enough data for age >75
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16
Q

2018 acc/aha guidelines- when to statins for primary prevention?

A
  1. Primary hypercholesterolemia - goal of 50% reduction in LDL
  2. DM
  3. Based on ASCVD Risk.
17
Q

Diabetes-specific risk factors? (6)

A
  1. Long duration of DM (10 year DM2)
    2, Albuminuria > 30
  2. G.F.R. <60
  3. Retinopathy
  4. Neuropathy
  5. A.B.I. <0.9
18
Q

Moderate intensity statins?

A

Atorvastatin - 10, 20mg
Fluvastatin- 80mg
Pitavastatin- 1, 2, 4 mg
Lovastatin- 40mg, 80mg
Pravastatin- 40, 80 mg
Rosuvastatin- 5, 10 mg
Simvastatin - 20, 40 mg (10 mg with ezetemibe)

19
Q

Which dietary component raises ldl-c?

A

Saturated fats

20
Q

Goal potassium intake to reduce hypertension & stroke?

A

3500 mg to 4700 mg

21
Q

What did the PREDIMED study show?

A

Mediterranean diet reduces CV death & disease by 30%

22
Q

Acc/aha 2019 primary prevention of CV disease - goal exercise minutes per week?

A

150 minutes

23
Q

USPSTF -goal exercise minutes per week?

A

150 minutes

24
Q

Success rate annually for smoking cessation?

A

4 to 6%

25
Q

5 A’s Model for Treating Tobacco Use

A

Ask about tobacco use
Advise to quit
Assess willingness to make a quit attempt
Assist in quit attempt
Arrange follow-up

26
Q

When to start bupropion S.R.?

A

1 to 2 weeks before quit date

27
Q

How to titrate up Zyban?

A

150 mg every morning for 3 days
Then 150mg twice daily

Time doses 8 hours apart