Primary Ciliary Dyskinesia Flashcards
1
Q
What is Kartagener syndrome?
A
Situs inversus
Pansinusitis
Bronchiectasis
2
Q
What are the three conditions that compose the classic presentation of PCD?
A
- Recurrent AOM
- Chronic sinusitis
- Bronchiectasis
3
Q
Why are males infertile in PCD?
A
Sperm immotility
4
Q
Why do females with PCD struggle with infertility?
A
Impacted functioning of the cilia in the fallopian tube
5
Q
How is PCD diagnosed?
A
Electron microscopy of respiratory cilia, obtained from scrapings/biopsy of nasal or airway epithelium
6
Q
In comparing PCD vs. CF, which condition typically has lower lobe infections vs. upper lobe infections first?
A
PCD = lower lobe infections (failure of the “escalator”)
CF = upper lobe infections
