Primary Care Update form 3rd year Flashcards

1
Q
Asthma:
diagnostic tests? (3)
why are objective tests important in asthma? (1)
when can't you diagnosis asthma? (1)
what to do in this age group? (2)
A
Objective asthma tests:
1- spirometry
2- FeNO
3- peak flow VARIABILITY - get diary 
(more on which to do when on another card)
  • commonly misdiagnosed
  • <5 years
  • treat symptoms based on clinical judgement
  • review on a regular basis
  • if they still have Sx at 5, do objective tests

if get to 5 and still unable to do test, then repeat every 6-12 months until satisfactory results obtained OR consider referral to specialise

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2
Q

Asthma:
what to ask in history? (7)
what will you hear on examination? (1)

A
  • wheeze
  • cough
  • SOB
  • diurnal variation
  • seasonal variation
  • triggers
  • PMH or FH of atopic disorders
  • occupation–> are Sx better on holiday/ away from work
  • expiratory polyphonic wheeze
    (if exam normal may still have asthma)
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3
Q

Ashtma:
what do FeNO tests do? (1)
positive spriometry test result for asthma? (2)

A
  • fractional exhaled nitric oxide (FeNO)
  • FEV1/FVC < 70%
  • bronchodilator reversibility test if obstructive spirometry,improvement of FEV1 of 12% is positive test
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4
Q
Asthma diagnosis:
diagnosis (2)
which test to do first? (1)
when to do FeNO? (1)
when to do PEFR variability? (1)
when might skin prick or specific IgE be appropraite? (1)
A
  • symptoms of asthma
    AND
    1- FeNO 35+ (kids) 40+ (adults) AND PEFR variability
    OR
    2- obstructive spirometry (FEV1/FVC<0.7) AND positive BDR
    (no other tests diagnostic e.g. total serum IgE/ skin prick!)
  • spirometry and bronchodilator reversibility (BDR)

FeNO if diagnostic uncertainty:

  • normal spirometry but symptoms
  • obstructive spirometry but negative BDR test
  • refer to specialist if negative FeNO and BDR, but positive spirometry (basicualy if the tests don’t match up)
  • do skin prick once diagnosis made to identify triggers
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5
Q

Asthma:
when to consider alternative diagnoses? (2)
differential diagnosis? (9)

A

if symptoms of asthma but

  • normal spirometry
  • FeNO <35ppb
  • negative peak flow variability

if any of these positive then still consider asthma as DD , repeat tests every 6 weeks & review symptoms

  • COPD
  • Bronchiectasis: sputum, coarse lung crepitations
  • Cystic fibrosis: moist cough, GI symptoms, clubbing, failure to thrive, Sx present from birth
  • Foreign body aspitations: acute, stridor, diminished breath sounds
  • GORD: cough, food-related symptoms, vomiting
  • Heart failure
  • TB
  • PE: acute, pleuritic pain, haemoptysis, crackles, sinus tacycardia, calf
  • Pertussis: paroxysms of coughing, vomiting, inspiratory whoop
  • Lung cancer: hoarse voice, haemoptysis, weight loss
  • Interstitial lung disease: dry cough, fine lung crepitations
  • Dysfunctional breathing: breathless, dizzy, light-headed, peripheral tingling
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6
Q

Asthma:

how does smoking affect FeNO? (1)

A
  • smoking lowers FeNO levels
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7
Q

Uncontrolled asthma:
what to consider? (5)
how often to review after starting new asthma medications? (1)
key points for prescribing ICS? (1)

A
1- alternative diagnosis
2- poor adherence
3- inappropriate inhaler technique
4- smoking (active or passive)
5- occupational exposures
6- psychosocial factors
7- seasonal/ environmental factors (e.g. triggers)
THEN consider adding drugs 
  • review in 4-8 weeks after starting medicines
  • adjust daily ICS dose over time; aim for lowest dose for effective control
    (to reduce side effects)
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8
Q

Asthma:
when to check they can use their inhaled? (5)
what is self-management in asthma? (3)

A
  • at every consultation relating to an asthma attack, in all care settings
  • when there is deterioration in asthma control
  • when the inhaler device is changed
  • at every annual review
  • if the person asks for it to be checked.
  • written personal action plan
  • education
  • when to seek emergency help
  • importance of asthma review
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9
Q

Asthma:
how to decrease maintenance therapy? (4)
drugs order? (5)
when to step up? (1)

A
  • step down in order stepped up
  • only reduce is Sx free for 3 months
  • discuss risks and benefits
  • follow-up
  • SABA (PRN)
  • low-dose ICS
  • LABA
  • high-dose ICS
  • OTHERS: theophyline, LTRA, LAMA and refer to specialist care
  • if 3+ SABA a week
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10
Q

NICE guidelines lung cancer 2-week referral:

  • urgent specialist referral (2)
  • urgent CXR
A
  • CXR findings suggesting of lung cancer
  • over 40 and unexplained haemoptysis

if over 40 and 2+ of the following unexplained symptoms or have smoked and 1 or more:
- cough
- fatigue
- SOB
- weight loss
- chest pain
- appetite loss
consider if:
- presistent or recurrent chest infection
- clubbing
- supraclavicular lymphadenopathy or persistent cervical lymphadenopathy
- chest signs consistent with lung cancer
- thrombocytosis

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11
Q

NICE guidelines mesothelioma 2-week referral:

key symptoms?

A
  • asbestos exposure
  • cough
  • fatigue
  • SOB
  • chest pain
  • weight loss
  • appetite loss
  • finger clubbing
  • chest signs/ pleural disease
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12
Q

NICE guidelines oesophageal cancer 2-week referral:
urgent referral for what one symptom? (1)
other red flag features? (concerning if a couple)

A

NB urgent means 2-weeks in guidance terms

  • dysphagia (URGENT REFERAL EVEN IF JUST DYSPHAGIA!)

weight loss and aged 55+ with:

  • upper abdo pain
  • reflux
  • dyspepsia
  • haematemesis
  • treatment-resistent dyspepsia non-urgent referral
  • upper GI pain
  • nausea
  • vomiting
  • reflux
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13
Q

NICE guidelines pancreatic cancer 2-week referral:
urgent referral for what one symptom? (1)
when to consider urgent CT (or US if CT unavailable)? (7)

A
  • aged 40+ and JAUNDICE

aged 60+ with weight loss and one of the following:

  • diarrhoea
  • back pain
  • abdo pain
  • nausea
  • vomiting
  • constipation
  • new-onset diabetes
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14
Q

NICE guidelines stomach cancer 2-week referral:
urgent referral for what one symptom? (1)
when to offer upper GI endoscopy?

A
  • upper abdo mass consistent with stomach cancer
  • same as oesophageal
    (dysphagia, upper abdo pain, reflux, dyspepsia, haematemasis, treatment-resistent dyspepsia, anaemia etc)
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15
Q

NICE guidelines colorectal cancer 2-week referral:

urgent referral symptoms?

A
  • 40+ and unexplained weight loss + abdo mass
  • 50+ and real bleeding
  • iron-deficiency anaemia +changes in bowel habit
  • mass
    (vague)
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16
Q

NICE endometrial cancer:

red flag features?

A
  • post-menopasual bleeding (especially if 12 months post last bleed)

US if:

  • unexplained vaginal discharge
  • haematuria
  • anaemia
  • high blood glucose levels
17
Q

NICE prostate cancer:

red flag features?

A
  • lower urinary tract symptoms
  • erectile dysfunction
  • haematuria
18
Q

NICE bladder cancer:

red flag features?

A
  • haematuria
  • unexplained non-visable haematuria and dysuria or raised WCC
  • recurrent, unexplained UTI

renal cancer has very similar symptoms

19
Q

NICE melanoma:

urgent referal for pigmented skin lesions?

A

weighted 7-point checklist of 3 points or more

MAJOR FEATURES (2 points each)
- change size
- irregular shape
- irregular colour
MINOR FEATURES (1 point each)
- >7mm
- inflammation
- oozing
- change in sensation
20
Q

NICE laryngeal cancer red flags? (2)

A

over 45 and:

  • persistent unexplained hoarseness or
  • unexplained lump in neck
21
Q

NICE leukaemia referral pathway:

urgent FBC red flags?

A
  • pallor
  • persistent fatigue
  • unexplained fever
  • unexplained/ recurrent infection
  • lymphadenopathy
  • unexplained bruising
  • unexplained bleeding
  • unexplained petechiae
  • hepatosplenomegaly
22
Q

What symptoms are concerning for cancer in a history? (3)

A
  • UNEXPLAINED weight loss
  • unexplained appetite decrease
  • DVT

https://www.nice.org.uk/guidance/ng12/resources/suspected-cancer-recognition-and-referral-pdf-1837268071621 - this document very good list at the end of symptoms and what action to take

23
Q
Type 2 diabetes:
who to test for type 2? (2)
who to encourage to have a risk assessment? (10)
what to do if low  risk score? (2)
what to do if high risk score? (2)
A

2 stages:
1- a validated risk assessment to see who should have a test
2- those high risk get blood test and lifestyle advice
(i.e. if you’re treating a patient who you think might be at risk then do risk assessment on them)

people in high risk groups:

  • cardiovascular disease
  • hypertension
  • obesity
  • stroke
  • polycystic ovary syndrome
  • PMH gestational diabetes
  • mental health problems
  • over 40 years old
  • ethnic minorities (aged 25-39)
  • learning disabilities
  • anyone attending ophthalmology, renal surgery, vascular surgery, and emergency assessment units
  • brief advice: encouragement & reassurance, discuss any at risk factors
  • reassess if condition changes, or max 5 years later
  • offer blood test to see if (pre) diabetes diagnosis
24
Q

Type 2 diabetes:
who to offer blood test to? (2)
what to do it moderate risk but negative for diabetes? (1)
what to do if high risk but negative? (1)

A
  • any adult with high risk score
  • aged 25 or over, Asian descent, BMI > 23 km/m2
  • retest in 3 years, advice
  • re-test in 1 year, advice
25
Q

Type 2 diabetes diagnosis? (1)

diangosis for gestational diabetes? (2)

A
diabetes symptoms 
\+ 
random plasma glucose >=11.1 mmol/l
OR
fasting plasma glucose conc. >=7.ommol/l
OR
2 hour plasma glucose conc. >=11.1 mmol/l two hours after 75g anhydrous glucose in oral glucose tolerance test (OGTT)

if no symptoms then needs two tests on two separate days

  • fasting glucose 5.6mmol/l +
  • 2-hour plasma glucose 7.8mmol/l+
26
Q
Diabetes:
key categories of management? (4)
what is the HbA1c target? (2)
what does it depend on? (3)
whats problem with very tight glucose control in the frail? (1)
A

1- education!
2- monitor blood glucose
3- monitor CVD/HTN/ high cholesterol
4-monitor complications

  • every 6 months
  • it’s FLEXIBLE
  • 3 main targets: 48, 53 and 58
  • depends on the patient e.g. personal choice/ if frail
  • what drugs they’re taking (if hypo risk)
  • life expectancy (if going to die in 6 months let them eat cake!)
27
Q

Diabeetes:

who should self-monitor blood glucose? (5)

A
  • on insulin
  • evidence hypoglycaemic episodes
  • on oral medication that may increase their risk of hypoglycaemia while driving or operating machinery
  • pregnant or planning to be pregnant
  • starting oral/ IV corticosteroids
  • to confirm suspected hypoglycaemia
  • risk vs benefit of hypoglycaemia and tight glucose control
28
Q

what affects drug choice? (

what non diabetic drugs would you want to consider prescribing? (2)

A
  • BMI e.g. might want them on one that reduces weight
  • HbA1c
  • kidney eGFR
  • age
  • occupation; e.g. for hypo risk
  • statin (cholesterol—> QRISK)
  • blood pressure –> BP drugs
29
Q

Type 2 diabetes:

HbA1c targets and managment levels? (4)

A

diet and lifestyle (D&L) at all levels

1 - >48mmol/mol
–> METFORMIN

2- D&L+ single drug > 48mmol/mol
or >54mmol/mol if hypo risk drug
–> ADD 2ND DRUG AND TAGET 53mmol/mol

3- D&L+ 2 drugs 58mmol/mol
–> ADD 3RD DRUG but keep target 53mmol/mol

4- D&L+ 3 drugs make personal target

30
Q

Who to suspect diabetes in?

A
  • recurrent cellulitis
  • candidiasis
  • dermatophyte infections
  • gangrene
  • pneumonia (particularly TB reactivation)
  • influenza
  • genitourinary infections (UTIs)
  • osteomyelitis
  • and/or vascular dementia