Primary Care Management of Common Mental Disorders Flashcards

1
Q

Most mental illness is managed exclusively where?

A

in primary care

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2
Q

what are the Depression Risk Factors?

A
  • Previous depression
  • History of other mental illness
  • History of substance misuse
  • Family history of depression or suicide
  • Domestic violence
  • Unemployment
  • Poor social support network
  • Recent stressful life event – eg losses, bereavement, losing job
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3
Q

Screening for depression:

Be alert to the possibility of depression, especially if what?

A
  • A PMH of depression.
  • Significant illnesses causing disability.
  • Other mental health problems, e.g. dementia.
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4
Q

Screening for depression:

what are 2 key questions to ask when screening for depression?

A

“During the last month, have you often been bothered by feeling down, depressed or hopeless?”

“During the last month, have you been bothered by having little interest or pleasure in doing things?”

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5
Q

There are two classification systems that allow us to diagnose depression – ICD10 and DSM5

what is the ICD -10 Diagnosis of depression?

A
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6
Q

what is the DSM IV/V diagnosis of depression?

This is what is used in NICE guidelines

Currently no SIGN guidelines on depression

A
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7
Q

NICE Depression Guidelines NICE 2018, CG90 & 91:

what is required for the diagnosis of depression?

A
  • Diagnosis should be based on DSM IV criteria
  • For depression: 5/9 criteria are required, including at least 1 of the first 2 criteria (low mood/anhedonia)
  • Subthreshold depressive symptoms are defined as those having <5 of the DSM IV criteria
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8
Q

NICE Depression Guidelines NICE 2018, CG90 & 91:

Severity is based on functional impairment, once the diagnostic criteria have been passed (i.e. once you have 5 or more symptoms, one of which must be from the first two criteria)

what is mild moderate and severe dperession?

A
  • Mild depression is 5 or more symptoms (one of which must be from the first two criteria) but with mild functional impairment
  • Severe depression is at least 5 symptoms (one of which must be from the first two criteria), and often most or all will be present) with marked functional impairment
  • Moderate severity falls between mild and severe
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9
Q

what screening tool is used for depression?

A
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10
Q

NICE 2018 Treatment Guidelines:

STEPPED CARE MODEL - The least intrusive intervention to be provided first. If that intervention is ineffective, or declined, offer an appropriate intervention from the next step

what is step 1 treatment of depression?

A

STEP ONE: recognition, assessment & initial management:

  • All known and suspected presentations of depression
  • Intervention options: Assessment, support, psycho-education, lifestyle advice, active monitoring and referral for further assessment and interventions
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11
Q

what is step 2 of depression treatment?

A

Step 2: recognised depression – persistent subthreshold depressive symptoms or mild to moderate depression

  • Offer advice on sleep hygiene
  • Offer active monitoring (discuss concerns, provide information about depression, reassess within 2w; contact the person if they do not attend follow-up appointment)
  • Low-intensity psychological and psychosocial interventions (e.g. individual self-help based on CBT principles, computerised CBT, group CBT, group physical activity programme)
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12
Q

treating depression:

Do not routinely use antidepressants (because risk–benefit ratio is poor), unless what?

A
  • They have a past history of moderate–severe depression OR
  • They present with subthreshold symptoms that have been present for 2y or more OR
  • They have subthreshold symptoms for <2y but they don’t respond to other interventions
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13
Q

what is step 3 of depression treatment?

A

Step 3: persistent subthreshold depressive symptoms or mild to moderate depression with inadequate response to initial interventions, and moderate and severe depression

  • an antidepressant (normally a selective serotonin reuptake inhibitor [SSRI])or
  • a high-intensity psychological intervention - Individual CBT, interpersonal therapy, behavioural activation, couples therapy where the relationship is a contributory factor
  • Combined treatments (medication + high intensity psychological) preferred for moderate to severe depression
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14
Q

what is behavioural activation?

A

In depression, people often stop doing the things they used to and become more withdrawn. This, in itself, reinforces low mood. In behavioural activation, patients are asked to look at the impact activities have on mood, and then to schedule activities to help improve mood. They can also look at the cognitive things that inhibit activity, such as rumination. It is easier to train both staff and patients to do behavioural activation, so it is cheaper than CBT.

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15
Q

____ is first line antidepressant in depression

A

SSRI

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16
Q

in depression what other things should you consider?

A

fitness for work - med 3 forms

fitness to drive

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17
Q

what follow up is reuqired for dementia treatment?

A
  • Normally see people 2 weeks after starting, at intervals of every 2 to 4 weeks for 3 months and then at longer intervals if the response is good
  • In patients aged under 30, or considered at greater risk, see after one week and as frequently thereafter as appropriate until risk considered no longer clinically important
  • Encourage to take for at least 6 months after remission, and for up to 2 years if they are at risk of relapse
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18
Q

Non responders:

If response absent or minimal after 3 to 4 weeks at therapeutic dose, increase level of support and increase dose OR switch to another antidepressant

how do you switch antidepressants?

A
  • Initially switch to a different SSRI or a better tolerated newer generation antidepressant
  • Subsequently to another class that may be less well tolerated e.g. TCA, venlafaxine or MAOI (MAOI specialist initiated only)
  • Combining and augmentation: Using combinations should only normally be started in primary care in consultation with a psychiatrist
  • Consider combining or augmenting an antidepressant with lithium (mood stabalizer), an antipsychotic (e.g. quetiapine, aripriprazole etc) or another antidepressant such as mirtazapine
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19
Q

Non responders:

If response absent or minimal after 3 to 4 weeks at therapeutic dose, increase level of support and increase dose OR switch to another antidepressant

how do you stop or reduce antidepressants?

A

Advise re risk of discontinuation symptoms and gradually reduce the dose, normally over a 4 week period (minimise the risk of developing discontinuations symptoms.)

Discontinuation symptoms - These include restlessness, irritability, anxiety, insomnia, unsteadiness, sweating, GI upset

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20
Q

what is step 4 of depression treatment? (severe and complex depression)

  • Severe and complex depression
  • Risk to life
  • Severe self-neglect
A

Refer for multiprofessional and possible inpatient care for people with depression who are at significant risk of self-harm, have psychotic symptoms, require complex multiprofessional care or where an expert opinion is needed

Other treatments, which are only offered in hospital, such as ECT, can be considered, which is a very effective treatment for severe depression.

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21
Q
  • Suicide is the biggest cause of _____ for:
  • Those aged 15–24y.
  • Men under 50y.
A

death

22
Q

it’s important Every time we do a mental state assessment, we assess for _______ risk

A

suicide

23
Q

what is involved in a suicide risk assessment?

A

The key risk factors to assess are:

Previous self-harm/suicidal behaviour

Depression and other mental health problems

Alcohol/drug misuse

Physical illness (note: those with traumatic brain injuries are at twice the risk of suicide as the general population)

Low socioeconomic status

Relationship breakdown

24
Q

10% of adults taking antidepressants for ‘depression’ actually have features of bipolar disorder

how should ou manage bipolar disorder?

A
  • Refer if suspected (to secondary care)
  • Do not start SSRIs in depressed phase – refer/discuss with 2ry care
  • Stop antidepressants if patients become hypomanic
  • Suicide risk in bipolar 20 times higher than general population
  • Beware sodium valproate in women of child-bearing age
  • 2ry care medication only – woman must be on effective contraception and signed agreement between prescriber and patient

Need treatment with mood stabilisers

25
Q

what are the different kinds of Anxiety Disorders?

A

Generalised Anxiety Disorder - Excessive worry about a number of different events. Can exist in isolation or comorbid anxiety/depressive disorders

Panic Disorder - Recurrent panic attacks and persistent worry about further attacks

Social Anxiety Disorder - persistent fear of, or anxiety about, one or more social or performance situations that is out of proportion to the actual threat posed by the situation

26
Q

Generalised Anxiety Disorder – DSM IV classification

A

A. Excessive anxiety and worry (apprehensive expectation), occurring more days than not for at least 6 months, about a number of events or activities (such as work or school performance)

B. The person finds it difficult to control the worry

C. The anxiety and worry are associated with three or more of the following six symptoms (with at least some symptoms present for more days than not for the past 6 months):

  • Restlessness or feeling keyed up or on edge
  • Being easily fatigued
  • Difficulty concentrating or mind going blank
  • Irritability
  • Muscle tension
  • Sleep disturbance (difficulty falling or staying asleep, or restless unsatisfying sleep)
27
Q

what is the Screening tool used to grade severity of anxiety?

A
28
Q

NICE Generalised Anxiety Disorder 2011, CG113
Step 1: Identification and assessment

what is involved?

A

If depression or other anxiety disorder present, treat the primary disorder first eg co-morbid depression/anxiety – treat depression first.

Treat co-morbid substance misuse disorder first

•For all identified with generalised anxiety disorder, offer the following treatment: education about anxiety disorder, and active monitoring of patient’s function and symptoms. Discourage over-the-counter treatments (lack of evidence, interactions).

29
Q

GAD:

Step 2: For those for whom active monitoring is insufficient

what is done?

A

Offer: Low-intensity psychological interventions

•Individual non-facilitated self-help: written material based on CBT principles, with instructions to work through material over at least 6 weeks

•Individual guided self-help: written material as above, with support from a trained practitioner who offers 5–7 weekly/fortnightly face-to-face/phone sessions lasting 20–30mins each

•Psychoeducational groups: usually 6 weekly sessions of 2 hours each with a group of patients and a therapist. Based on CBT principles; interactive and including self-help manual

30
Q

GAD management:

Step 3: For those with marked functional impairment OR for those who have not improved with step 2 treatments

what is done?

A

High intensity psychological or medication

31
Q

GAD treatment:

Step 4: Specialist (CMHT) referral. Consider referral to step 4 if what?

A
32
Q

what is Panic Disorder - DSM Classification?

A

Recurring unforeseen panic attacks, followed by at least a month of persistent worry about having another attack and concern about its consequences OR a significant change in behaviour related to the panic attacks.

33
Q

Panic attacks are characterized by an abrupt surge of intense fear or physical discomfort, reaching a peak within a few minutes, in which at least 4 of the following symptoms are present:

A
34
Q

NICE Panic Disorder NICE 2011, CG113:

what is the treatment if Mild- Moderate?

A
  • Self-help
  • Offer bibliotherapy based on CBT principles
  • Offer information on support groups.
  • Discuss the benefits of exercise as part of good general health
  • Review progress appropriately based on individual circumstances (often every 4–8w)
35
Q

NICE Panic Disorder NICE 2011, CG113:

what is the treatment if Mod- Severe?

A
  • Psychological therapy
  • 1–2 hourly sessions weekly. These should be completed within 4 months. 7–14h is usually optimal. Sometimes, more intense CBT over a shorter timeframe may be appropriate
  • Drug treatment
36
Q

what drug treatment is used in panic disorder?

A
  • Offer an SSRI licensed for panic disorder (citalopram, sertraline, paroxetine, escitalopram but NOT fluoxetine (as shown not to be effective)
  • If unable to use SSRI or no response after 12w, consider imipramine or clomipramine (off-label indication for both) – beware both are dangerous in overdose. (TCA)
  • Avoid benzodiazepines/sedating antihistamines/antipsychotics
  • If one therapy (CBT, drugs, self-help) fails to give adequate response, try an alternative from this list; if no response, refer for specialist input (CMHT)
37
Q

what is seen in Social Phobia - DSM?

A
38
Q

NICE Social Anxiety Disorder 2013, CG150

whata re some useful screning questions?

A
  • Do you find yourself avoiding social situations or activities?
  • Are you fearful or embarrassed in social situations?
39
Q

NICE Social Anxiety Disorder 2013, CG150

what is the treatment?

A

1st line: CBT

2nd line: Medication

  • sertraline or escitalopram
  • Continue for 6 months of treatment once treatment has become effective
40
Q

Differentiating grief from depression - what is experinced in grief?

A
  • Grief includes longing/yearning for the loved one
  • positive emotions can still be experienced
  • symptoms worst when thinking about the deceased person
  • people often want to be with others, whereas people with depression tend to want to be alone
41
Q

what is Prolonged Grief Disorder?

A
  • Marked distress and disability caused by the grief reaction
  • AND the persistence of this distress and disability more than 6m after a bereavement
42
Q

what is the treatment of Prolonged Grief Disorder?

A
  • Counselling eg Cruse
  • Antidepressants for comorbid depression
  • Behavioural/cognitive/exposure therapies
  • Refer if significant impairment in functioning
43
Q

OCD Diagnosis:

•OCD is characterised by obsessions or compulsions (usually both) which must impair function

what are obsessions and compulsions?

A
  • Obsessions: unwanted intrusive thoughts, images or urges. Tend to be repugnant and inconsistent with a person’s values
  • Compulsions: repetitive behaviours or mental acts the person feels driven to perform. Can be overt (checking they locked the door) or covert (mentally repeating a phrase in their head)
  • To warrant a diagnosis of OCD, obsessions and compulsions must be time consuming >1hr , or cause significant distress or functional impairment
44
Q

how do you screen for Obsessive Compulsive Disorder?

A
  • Do you wash or clean a lot?
  • Do you check things a lot?
  • Is there any thought that keeps bothering you that you’d like to get rid of and can’t?
  • Do your daily activities take a long time to finish?
  • Are you concerned about putting things in a special order? Are you very upset by mess?
  • Do these problems trouble you?
45
Q

what is the treatment of OCD?

A
  • 1st line: CBT including Exposure and Response Prevention (asking people to resist their urges/compulsions)
  • 2nd line: Medication ; SSRIs (sertraline/citalopram/fluoxetine/paroxetine) - Often required at higher doses for longer duration - up to 12 weeks to see a response
  • 3rd line: Medication; clomipramine (most SSRI like of tricyclics)
46
Q

Insomina:

  • Common GP problem
  • 12% of over 65s were prescribed benzodiazepines or Z-drugs. (BJGP 2016;66(647):e410)

Screen for 2ry causes - what are they?

A
  • Anxiety/depression.
  • Physical health problems (e.g. pain, dyspnoea)
  • Obstructive sleep apnoea (risk increased if BMI ≥30 or neck circumference ≥40cm)
  • Excess alcohol or illicit drugs
  • Parasomnias (restless legs, sleep walking/talking/sleep terrors/teeth grinding (bruxism), etc.)
  • Circadian rhythm disorder (especially in shift workers)
47
Q

what are the treatments of insomina?

A
48
Q

how are eating disorders managed?

A

•Recognise and Refer to 2ry care

49
Q

Emerging Psychosis - how is it delt with in primary care?

A
  • Average GP sees one case a year
  • Easy to spot if frank psychosis
  • Often difficult to diagnose in early stages
  • Listen to family concerns
  • Look for increasing distress and declining function
  • Consider organic cause
  • Early diagnosis improves prognosis
50
Q

Shared Care for Major Mental illness - what is involved?

A
  • Medication monitoring
  • BMI/BP/smoking
  • Blood tests:
  • Antipsychotics - cardiovascular risk factors
  • Lithium (bipolar/adjunct in depression):
  • Thyroid / Kidney function tests 6 monthly
  • Lithium levels 3 monthly – risk of lithium toxicity
51
Q

what is the role of 3rd sector organisations?

A

Involved in supporting our patients in the community

52
Q

Summary:

  • Mental illness is _______
  • Mental illness is _______
  • Important to _______ signs and symptoms of mental illness
  • Investigate ______ available resources for signposting patients
  • Do not be afraid to ask for ____
A

common

treatable

identify

locally

help