Primary Bone Tumors

Question 1

• Abuts the articular surface (in long bones) - Well defined with a nonsclerotic margin (in long bones)

Answer 1

Giant cell tumor

Question 2

Multiple enchondromas

Answer 2

Ollier disease

Question 3

Classic description is that is has a ground-glass or smoky matrix

Answer 3

Fibrous dysplasia

Question 4

Any bone lesion in a patient older than 40 should have ___________ as a consideration

Answer 4

metastatic disease

Question 5

the only primary tumor that virtually never presents with blastic metastatic disease is

Answer 5

renal cell carcinoma

Question 6

• Older than age 40 - Bubbly, lytic bone lesions

Answer 6

Myeloma

Question 6

Also called simple bone cysts or unicameral bone cysts

Answer 6

Solitary bone cyst

Question 6

Lytic malignant lesions that do not produce osteoid or chondroid matrix

Answer 6

Fibrosarcoma

Question 7

It has been said that if a lesion grows in the long axis of a long bone, rather than being circular, it is

Answer 7

benign

Question 8

Subperiosteal bone resorption is pathognomic

Answer 8

Hyperparathyroidism (brown tumor)

Question 9

(+) Fallen fragment sign

Answer 9

Solitary bone cyst

Question 9

A neoplasm with a radiologic appearance identical to that of ewing sarcoma that is, a permeative or motheaten pattern

Answer 9

Primary Lymphoma of the bone

Question 9

A benign joint lesion that probably occurs from metaplasia of the synovium and leads to multiple calcific loose bodies in a joint

Answer 9

Synovial osteochondromatosis

Question 10

The only lesions that demonstrate bone sequestra are?

Answer 10

infection, EG, lymphoma and fibrosarcoma

Question 12

They are expansile, having soap-bubble appearance; Commonly occur in the posterior elements of the vertebral bodies

Answer 12

Osteoblastoma

Question 13

possible primary malignant bone tumors at age > 40

Answer 13

Chondrosarcoma, metastatic disease, meloma

Question 14

Presence of bone scalloping

Answer 14

Enchondroma

Question 15

Other name for Desmoid tumor

Answer 15

desmoplastic fibroma or aggressive fibromatosis

Question 16

-A half-grade fibrosarcoma -Most commonly arise in the soft tissues and are uncommon in the bony skeleteon

Answer 16

Desmoid tumor

Question 16

The two most common soft tissue tumors

Answer 16

malignant fibrous histiocytoma and liposarcoma

Question 17

The most reliable plain film indicator for bening vs. malignant lesions

Answer 17

Zone of transition

Question 18

A common location of Parosteal osteosarcoma is the?

Answer 18

posterior femur

Question 20

• Younger than age 30 - Epiphyseal only

Answer 20

Chrondroblastoma

Question 22

Has a wide variety of manifestations which can mimic other pathologie

Answer 22

Eosinophilic granuloma

Question 23

because of a low-grade chronic irritation that gives the periosteum time to lay down thick new bone and remodel into more normal cortex

Answer 23

Benign Periostitis

Question 24

 Four aspects of a lesion to be examined (Brant):

Answer 24

o Cortical destruction o Periostitis o Orientation or axis of the lesion o Zone of transition

Question 24

possible primary malignant bone tumors at age 1 -30

Answer 24

Ewing sarcoma, osteogenic sarcoma

Question 25

possible primary malignant bone tumors at age 30-40

Answer 25

Giant cell tumor, parosteal sarcoma, fibrosarcoma, malignant fibrous histiocytoma, lymphoma of bone

Question 26

\_\_\_\_\_\_\_\_\_\_\_\_ should be considered in the diagnosis any time there is a bony of soft tissue mass with amorphous, snowflake calcification in an older patient (\>40 years)

Answer 26

Chondrosarcoma

Question 27

Benign synovial soft tissue process that causes joint swelling and pain and, occasionally, joint erosions

Answer 27

Pigmented villonodular synovitis

Question 28

Originates from the periosteum of the bone and grows outside the bone; Often wraps around the diaphysis without breaking through the cortex

Answer 28

Parosteal osteosarcoma

Question 29

Presence of multiple lesions of fibrous dysplasia in the jaw

Answer 29

cherubism

Question 31

A very poor determinant of benign vs. aggressive lesions

Answer 31

Orientation or axis of the lesion

Question 32

Periosteum has no time to consolidate; Appears lamellated (onion-skinned) or amorphous or even sunburst-like

Answer 32

Aggressive Periostitis

Question 33

Most common malignant primary bone tumor

Answer 33

Osteosarcoma

Question 34

Have a variable appearance that makes it difficult to diagnose; Most commonly occur in patients older than age 40

Answer 34

Chondrosarcoma

Question 35

Lytic lesions with variations extending from permeative to fairly well defined

Answer 35

Malignant Fibrous Histiocytoma

Question 36

Often have phleboliths associated with them and often cause cortical holes in adjacent bone that can mimic a permeative or moth-eaten pattern in a pseudopermeative pattern

Answer 36

Hemangioma

Question 37

The most common benign cystic lesion in the phalanges

Answer 37

Enchondroma

Question 37

A lesion consisting of multiple small holes is said to be

Answer 37

permeative

Question 38

Defined as the border of the lesion with the normal bone

Answer 38

Zone of transition

Question 40

The most common bone lesion encountered by radiologists

Answer 40

Non-ossifying fibroma

Question 42

Multiple enchondromas associated with soft tissue hemangiomas

Answer 42

Maffucci syndrome

Question 43

Eccentrically located; Sharply defined zone of transition

Answer 43

Giant cell tumor

Question 44

Expansile; Younger than age 30; Typically present because of pain; they often occur in the posterior elements of the spine

Answer 44

Aneurysmal bone cyst

Question 46

Malignant Giant Cell tumors

Answer 46

Fibrosarcoma Malignant Fibrous Histiocytoma Desmoid tumor Primary Lymphoma of the bone

Question 47

Classically a permeative lesion in the diaphysis of a long bone in a child (primarily in children and adolescents)

Answer 47

Ewing Sarcoma

Question 48

one of the only lesions that is not characteristically hot on a radionuclide bone scan

Answer 48

Myeloma