Primary And Secondary Structure Of Proteins Flashcards

1
Q

What is the primary structure of a protein?

A

The linear sequence of amino acids in a protein.

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2
Q

What bonds hold together the amino acids in the primary structure of a protein?

A

Peptide bonds.

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3
Q

True or False: The primary structure of a protein determines its overall shape and function.

A

True

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4
Q

What is the secondary structure of a protein?

A

The regular, repeating patterns of folding of the protein chain.

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5
Q

What are the two main types of secondary structure in proteins?

A

Alpha helix and beta sheet.

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6
Q

In an alpha helix, the protein chain is coiled like a ________.

A

Spring.

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7
Q

In a beta sheet, the protein chain forms a __________ structure.

A

Flat, sheet-like.

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8
Q

True or False: Secondary structure of a protein is stabilized by hydrogen bonds.

A

True

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9
Q

What amino acid is often found in turns between secondary structure elements in proteins?

A

Proline.

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10
Q

What is a beta turn or beta bend in protein secondary structure?

A

A sharp turn in the protein chain that reverses direction.

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11
Q

What is a loop or coil in protein secondary structure?

A

A region that does not form regular secondary structure.

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12
Q

What is a random coil in protein secondary structure?

A

A disordered region of the protein chain.

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13
Q

What secondary structure element is often found in the turns of a protein chain?

A

Beta turns.

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14
Q

What is a secondary structure motif in proteins?

A

A combination of secondary structure elements forming a recognizable pattern.

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15
Q

What is a protein domain in terms of secondary structure?

A

A distinct structural unit within a protein that may fold independently.

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16
Q

What is a supersecondary structure in proteins?

A

A combination of secondary structure elements that form a functional unit.

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17
Q

What is a protein fold in terms of secondary structure?

A

A specific arrangement of secondary structure elements that forms a stable unit.

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18
Q

True or False: The secondary structure of a protein is determined by the primary structure.

A

True

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19
Q

What techniques are commonly used to study protein secondary structure?

A

X-ray crystallography, NMR spectroscopy, and circular dichroism.

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20
Q

What is the Ramachandran plot used for in protein structure analysis?

A

To analyze the allowed regions of phi and psi angles in protein structures.

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21
Q

What is a helix-coil transition in protein secondary structure?

A

The transition between helical and disordered states in a protein.

22
Q

What is a helix-turn-helix motif in protein secondary structure?

A

A common DNA-binding motif consisting of two alpha helices separated by a turn.

23
Q

What is a beta hairpin in protein secondary structure?

A

A short anti-parallel beta sheet structure with a hairpin loop.

24
Q

What is a helix-loop-helix motif in protein secondary structure?

A

A common DNA-binding motif consisting of two alpha helices separated by a loop.

25
Q

What is a beta-alpha-beta motif in protein secondary structure?

A

A structural motif composed of a beta strand, alpha helix, and another beta strand.

26
Q

What is the primary structure of a protein?

A

The linear sequence of amino acids in a protein.

27
Q

What bonds hold together the amino acids in the primary structure of a protein?

A

Peptide bonds.

28
Q

True or False: The primary structure of a protein determines its overall shape and function.

A

True

29
Q

What is the secondary structure of a protein?

A

The regular, repeating patterns of folding of the protein chain.

30
Q

What are the two main types of secondary structure in proteins?

A

Alpha helix and beta sheet.

31
Q

In an alpha helix, the protein chain is coiled like a ________.

A

Spring.

32
Q

In a beta sheet, the protein chain forms a __________ structure.

A

Flat, sheet-like.

33
Q

True or False: Secondary structure of a protein is stabilized by hydrogen bonds.

A

True

34
Q

What amino acid is often found in turns between secondary structure elements in proteins?

A

Proline.

35
Q

What is a beta turn or beta bend in protein secondary structure?

A

A sharp turn in the protein chain that reverses direction.

36
Q

What is a loop or coil in protein secondary structure?

A

A region that does not form regular secondary structure.

37
Q

What is a random coil in protein secondary structure?

A

A disordered region of the protein chain.

38
Q

What secondary structure element is often found in the turns of a protein chain?

A

Beta turns.

39
Q

What is a secondary structure motif in proteins?

A

A combination of secondary structure elements forming a recognizable pattern.

40
Q

What is a protein domain in terms of secondary structure?

A

A distinct structural unit within a protein that may fold independently.

41
Q

What is a supersecondary structure in proteins?

A

A combination of secondary structure elements that form a functional unit.

42
Q

What is a protein fold in terms of secondary structure?

A

A specific arrangement of secondary structure elements that forms a stable unit.

43
Q

True or False: The secondary structure of a protein is determined by the primary structure.

A

True

44
Q

What techniques are commonly used to study protein secondary structure?

A

X-ray crystallography, NMR spectroscopy, and circular dichroism.

45
Q

What is the Ramachandran plot used for in protein structure analysis?

A

To analyze the allowed regions of phi and psi angles in protein structures.

46
Q

What is a helix-coil transition in protein secondary structure?

A

The transition between helical and disordered states in a protein.

47
Q

What is a helix-turn-helix motif in protein secondary structure?

A

A common DNA-binding motif consisting of two alpha helices separated by a turn.

48
Q

What is a beta hairpin in protein secondary structure?

A

A short anti-parallel beta sheet structure with a hairpin loop.

49
Q

What is a helix-loop-helix motif in protein secondary structure?

A

A common DNA-binding motif consisting of two alpha helices separated by a loop.

50
Q

What is a beta-alpha-beta motif in protein secondary structure?

A

A structural motif composed of a beta strand, alpha helix, and another beta strand.