Preterm birth

Question 1

Late preterm birth

Answer 1

Deliveries prior to 37 weeks

Question 2

Very preterm birth

Answer 2

Deliveries prior to 32 weeks

Question 3

Extremely preterm birth

Answer 3

Deliveries prior to 28 weeks

Question 4

Germinal matrix intraventricular haemorrhages (GM-IV)

Answer 4

Involves bleeding in the germinal matrix, a transient structure within the developing brain located along the floor of the lateral ventricles.

Question 5

What is false about the grades of GM-IVH?

I. They are graded according to severity
II. The higher graded forms lead to cPVL
III. Grades 3 and 4 increase the risk for cerebral palsy
IV. Haemorrhages usually occur secondary to blood pressure fluctuations soon after birth

Answer 5

II is false, the more severe forms lead to PHI

Question 6

Periventricular haemorrhagic infarction (PHI)

Answer 6

A more severe form of haemorrhage. It conveys a risk of serious neurological and intellectual compromise, often including spastic diplegia

Question 7

Cystic periventricular leukomalacia (cPVL)

Answer 7

A non-haemorrhagic injury involving necrosis in the periventricular region, seccondary to hypoxia-ischaemia or cerebrovascular inflammation in an immature central nervous system