Pressure/ Blood Flow/ ISCH disease Flashcards

1
Q

what is the function of arteries

A

they are low resistances vessels conducting blood to the various organs with little loss in pressure.

they act as pressure reserviurs for maintaining blood flow between ventricular contraction

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2
Q

name the 3 features of arteriorlies

A

major site of blood flow resistance

responsible for the pattern of blood flow distribution

particiapte in the regulation of arterial blood pressure

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3
Q

What is the fuction of capillaries

A

site of exchange between the blood and tissue

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4
Q

what is the function of the veins

A

low resistance vessels for blood flow back to the heart

capaity for blood is adjusted to facilitate flow

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5
Q

lable the diagram:

elastic fibers,endothelium,

tunica externa, tunica media/ tunica intima

smooth muscles, internal elastic membrane, external elastic membrane

A
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6
Q

Give the features of the following

Arteries/

Arterioles

Capillaries

Veins

A

1) thick, elastic, large lumen radius
2) hihgly muscular, well innervated walls, small lum radius
3) thin walled, large total cross sectional area
4) thin walled, hihgly distensible, large lumen radius

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7
Q

what 3 things does haemodynamics arise from

A

Pressure , Flow & resistance

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8
Q

define hydrostatic pressure

A

the pressure exerted by a fluid

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9
Q

what are the units of flow and pressure differnce

A

1) liters/min or ml/min
2) mmHg- millimeter of mercury

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10
Q

what is the equation for flow rate

A

Flow rate (l/min)= change in pressure (mmHg)/ resistance of blood vessels (mmHg’min/l)

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11
Q

what is the relationship between flow and Change in pressure

A

it is directly proportianal to one another

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12
Q

Flow rate depends on

A

Flow rate depends on the pressure difference NOT the absolute pressure

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13
Q

resistance is the measure of

A

friction impedeing flow

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14
Q

what is the shape that the distribution of the speeds of flow across a circular tube

A

it is parabolic

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15
Q

name the 3 factors that resistance depends on

A
  1. viscosity of the blood
  2. vessel lenght
  3. vessel radius- slight change can cause a notable change in flow
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16
Q

is the radius is increased by 2 times how much is the resistance increased by

A

16 times as much

17
Q

link radius with resistance and flow

A

Resistance= 1/r^4 Therefore

Flow= r^4

18
Q

what is Poiseuilles equation

A

Flow rate=

(πΔPr^4)/8ηL

π= Pie

ΔP= change in pressure

r^4= radius to the power of 4

η= viscosity

L= leght of the vessel

19
Q

what does arterial pressure fluctuate bc of

A

ventricular systole and diastole

20
Q

Mean arterial pressure is worked out how

A

Mean arterial pressure = diastolic pressure + 1/3 pulse pressure

21
Q

what are arteries known as

A

pressure reservoir

22
Q

what happens to the velocitry of flow and total cross sectional area

A

velocity of flow decreases as it goes from aorta to capillarires and from venules/ veins to vena cava it increases

the total cross sectional area increases from arteries to capillaries then decreases therefore the relationship is linked.

23
Q

why are arterioles major resistance vessles ?

A

small radius offers a lot of resistance and therefore reduce blood flow by alot. this drives the blood from the heart to the capillary beds.

24
Q

what is speical about arteriolar walls

A

thick layer of smooth muscle richly innverated by nerves of the sympathetic nervous system- sensitve to chemcail changes and certain cirulating hormones.

25
what does smooth muscle contraction and relaxation do regarding diamtere of the arteriols
contraction= decreased radius---\> increased resistances ---\> decreased local blood flow= **vasconstriction** Relaxation= increased radius ---\> decreased resistance= increased blood flow= **vasodilation**
26
what is vascular tone
arteriolar smooth muscle displays a state of partial constriction known as vascuolar tone.
27
name the 2 factors responsible for vascular tone and why is it important
myogenic activity sympathetic activity tonic activity makes it possibel for vasodilation/constriction