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ICU > Pressors > Flashcards

Pressors Flashcards

1
Q

What is the primary effect of α-1 adrenergic receptors?

A

Vasoconstriction

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2
Q

What are the primary effects of β-1 receptors?

A

Chronotropy and inotropy

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3
Q

What is the primary effect of β-2 receptors?

A

Vasodilation

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4
Q

What is the primary effect of most subtypes of dopamine receptors?

A

Vasodilation

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5
Q

What is the first-line pressor for septic shock?

A

norepinephrine

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6
Q

Which receptors does NE act on?

A

α-1 and β-1

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7
Q

What are the primary effects of NE?

A

vasoconstriction and a modest increase in CO

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8
Q

Which receptors does phenylephrine act on?

A

almost purely α-1

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9
Q

What are the primary effects of phenylephrine?

A

vasoconstriction (minimal cardiac inotropy or chronotropy

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10
Q

What is a potential disadvantage of phenylephrine?

A

decreased stroke volume

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11
Q

What receptors does Epi act on?

A

primarily β-1 + moderate β-2 and α-1

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12
Q

What is the effect of Epi at low doses?

A

Increased CO w/ no change (or decrease) in SVR

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13
Q

What is the effect of Epi at higher doses?

A

increased CO + increased SVR

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14
Q

What are the risks of Epi?

A

dysrhythmias and splanchnic vasoconstriction

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15
Q

What receptors does dopamine act on in low doses (1-2 mcg/kg/min)?

A

dopamine-1

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16
Q

What is the effect of dopamine at low doses?

A

splanchnic vasodilation

17
Q

What receptors does a medium dose of dopamine act on?

A

β-1

18
Q

What is the effect of medium-dose dopamine?

A

increased CO

19
Q

What receptors does high-dose dopamine act on?

A

α-1

20
Q

What is the predominant effect of high-dose dopamine?

A

vasoconstriction

21
Q

What is the main risk of dopamine?

A

tachyarrhythmias

22
Q

What is a reason why you might use dopamine over NE?

A

bradycardia

23
Q

What receptors does dobutamine act on predominantly?

A

β-1

24
Q

What is the effect of dobutamine?

A

increased CO and reduced SVR

25
Q

What is the primary effect of isoproterenol?

A

increased chronotropy

26
Q

What pressor would be good for a patient with septic shock and tachyarrhythmias?

A

phenylephrine

27
Q

What agent should be added (say to NE) for septic shock when the adrenergic effect is insufficient?

A

vasopressin

28
Q

What is the first-line pressor for hypodynamic shock?

A

NE

29
Q

What is the first-line pressor for anaphylactic shock?

A

Epi

ICU (1 decks)

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