Presentation Key Facts Flashcards
Cases of depression, aggressions and violent behaviour have been reported by users of
Anabolic androgenic steroids
In males: AAS results in thinning of the brain cortex and has a high impact on anti-social behaviour
In females: AAS results in thickening of the brain cortex and has a low impact on anti-social behaviour
Ovarian steroid hormones have different effects
Estrogen has a positive effect on hippocampus neurogenesis, and dendritic morphology in females. Progesterone has a negative effect on the estrogen induced cell multiplication in females
Glucocorticoids are used for autoimmune disease or chronic inflammation but excessive use can lead to
Immuno-deficiency
Comorbidity is the presence of one or more additional conditions often coo curing with a primary condition. In Parkinson’s disease, females tend to experience more comorbidities and non motor symptoms than men, although men…
Are more likely to have sexual dysfunction likely due to protective effects of estrogen
Men and women both experience hallucinations
Medications for pain management and motor symptoms are_____for men and women with Parkinson’s disease. Medications increase_____ concentrations and the possibility for addition exists
The same
Dopamine
Parkinson’s affects men____ as much as women and it linked to being caused by both _____ and _____ factors
Twice
Genetic and environments
(Neurotoxic pollutants and lysosome- related gene mutation)-main cause
Puberty is when
A child’s body starts to change physically and hormonal. It is different for boys and girls
Females ____ faster than males due to the possible of genetic, social, cross-cultural or delayed/ early pubescent factors
Mature
Synthetic estrogen such as those in dairy products have altering affected on____
Female development including earlier puberty, menstruation and maturation
Higher levels of estrogen were found to ______ sensitivity to pain while higher levels of testosterone tend to ____ this sensitivity
Increase
Lower
During pain, women and men show______ areas of brain activation
Different
Women: greater activity in the midcingulate cortex and insula
Men: greater activity in the supplementary motor area and eft caudate
Pain threshold
Pain tolerance
The point at which one starts to feel pain by a stimulus
The maximum amount of pain a person can tolerate before they are unable to continue under the stimulus
The endocannabinood system consists of receptors that cannabis can bind to including
CB1 receptors: primarily in the CNS
CB2 receptors: primarily in immune cells
Cannabis does alter the ________ of both men and women which can affect fertility
Hypothalamic-pituitary- gonadal axis
Due to ethical/ legalization issues there is not enough conclusive research on cannabis and fertility facts
- in Canada: cannabis was legalized on oct 17th, 2018
- approximately 20% of Canadians 15+ reported using cannabis in the last 3 months
- overall, more males use cannabis than females and begin using at a younger age
ASD yes s predominantly diagnosed in ___
Males (4 males: 1 female)
Females with ASD are often undiagnosed due to
Compensating behaviour and symptom camouflage
Individuals with ASD have a much ____ life expectancy due to ____
Lower
Comorbid illnesses and lack of healthcare expertise
An ASD diagnosis is important to ensure
Proper treatment, better overall quality of life and longevity
The major risk factors of Parkinson’s disease are
- Gender
Men more than women since estrogen delays onset of PD in women
- Age
Greater in older age
Individuals with Parkinson’s disease would see a decrease in ____ neurons in their brain, which is a hormone that controls movement and coordination
Dopamine
_____is found to be vital in the preservation of nigral dopaminergic neruons but it is still found to be very controversial
Estrogen
Carbidopa-levodopa medication is most effective approach for treatment of
Parkinson’s disease
Xenobiotic
A chemical which is often synthetic that is foreign to the body of a living organism
Xenobitoics include
Acetaminophen (Tylenol), pars bens and phthalates (cosmetics)
Parabens are considered _______
Xenoestrogens thus mimic hormones such as estrogen and testosterone by binding to receptors and sending unintended signals
Xenobiotics discussed can lead to
Pregnancy disorders such as preterm birth, preeclampsia, and glucose disorders
Also increase risk for disorders or the reproductive system such as cryptorchidism and infertility in males, as well as breast cancer and endometriosis
